[HTML][HTML] The role of the hypothalamic-pituitary-adrenal axis in depression across the female reproductive lifecycle: current knowledge and future directions

L Hantsoo, KM Jagodnik, AM Novick… - Frontiers in …, 2023 - frontiersin.org
The aim of this narrative review is to consolidate knowledge on the role of the hypothalamic-
pituitary-adrenal (HPA) axis in depression pathophysiology at different reproductive stages …

Adverse effects of early-life stress: focus on the rodent neuroendocrine system

SH Lee, EM Jung - Neural Regeneration Research, 2023 - journals.lww.com
Early-life stress is associated with a high prevalence of mental illnesses such as post-
traumatic stress disorders, attention-deficit/hyperactivity disorder, schizophrenia, and anxiety …

[HTML][HTML] Perspectives on adaptive dynamical systems

J Sawicki, R Berner, SAM Loos, M Anvari… - … Journal of Nonlinear …, 2023 - pubs.aip.org
Adaptivity is a dynamical feature that is omnipresent in nature, socio-economics, and
technology. For example, adaptive couplings appear in various real-world systems, such as …

Hormone seasonality in medical records suggests circannual endocrine circuits

A Tendler, A Bar… - Proceedings of the …, 2021 - National Acad Sciences
Hormones control the major biological functions of stress response, growth, metabolism, and
reproduction. In animals, these hormones show pronounced seasonality, with different set …

Dynamics of thyroid diseases and thyroid‐axis gland masses

Y Korem Kohanim, T Milo, M Raz, O Karin… - Molecular Systems …, 2022 - embopress.org
Thyroid disorders are common and often require lifelong hormone replacement. Treating
thyroid disorders involves a fascinating and troublesome delay, in which it takes many …

[HTML][HTML] The therapeutic effects of saikosaponins on depression through the modulation of neuroplasticity: From molecular mechanisms to potential clinical …

S Chen, K Wang, H Wang, Y Gao, K Nie, X Jiang… - Pharmacological …, 2024 - Elsevier
Depression is a major global health issue that urgently requires innovative and precise
treatment options. In this context, saikosaponin has emerged as a promising candidate …

[HTML][HTML] The association between dysbiosis and neurological conditions often manifesting with chronic pain

M Garvey - Biomedicines, 2023 - mdpi.com
The prevalence of neurological conditions which manifest with chronic pain is increasing
globally, where the World Health Organisation has now classified chronic pain as a risk …

New form of addiction: An emerging hazardous addiction problem of milk tea among youths

D Qu, X Zhang, J Wang, B Liu, X Wen, Y Feng… - Journal of affective …, 2023 - Elsevier
Background Milk tea has experienced tremendous growth in popularity in China, especially
among youths. The primary objective of this study is to investigate whether milk tea addiction …

[HTML][HTML] Major depressive disorder and bistability in an HPA-CNS toggle switch

B Ron Mizrachi, A Tendler, O Karin, T Milo… - PLOS Computational …, 2023 - journals.plos.org
Major depressive disorder (MDD) is the most common psychiatric disorder. It has a complex
and heterogeneous etiology. Most treatments take weeks to show effects and work well only …

Sex differences in androgen receptor, estrogen receptor alpha, and c-Fos co-expression with corticotropin releasing factor expressing neurons in restrained adult mice

KA Rybka, JJ Lafrican, ZJ Rosinger, DO Ariyibi… - Hormones and …, 2023 - Elsevier
Gonadal hormone actions through androgen receptor (AR) and estrogen receptor alpha
(ERα) regulate sex differences in hypothalamic-pituitary-adrenal (HPA) axis responsivity and …