G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy
E Ruggiero, SN Richter - Nucleic acids research, 2018 - academic.oup.com
Abstract G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …
form within guanine-rich strands of regulatory genomic regions. G4s have been extensively …
A guide to computational methods for G-quadruplex prediction
E Puig Lombardi, A Londoño-Vallejo - Nucleic acids research, 2020 - academic.oup.com
Guanine-rich nucleic acids can fold into the non-B DNA or RNA structures called G-
quadruplexes (G4). Recent methodological developments have allowed the characterization …
quadruplexes (G4). Recent methodological developments have allowed the characterization …
Re-evaluation of G-quadruplex propensity with G4Hunter
A Bedrat, L Lacroix, JL Mergny - Nucleic acids research, 2016 - academic.oup.com
Critical evidence for the biological relevance of G-quadruplexes (G4) has recently been
obtained in seminal studies performed in a variety of organisms. Four-stranded G …
obtained in seminal studies performed in a variety of organisms. Four-stranded G …
Detection of genomic G-quadruplexes in living cells using a small artificial protein
Abstract G-quadruplex (G4) structures formed by guanine-rich nucleic acids are implicated
in essential physiological and pathological processes and serve as important drug targets …
in essential physiological and pathological processes and serve as important drug targets …
G-quadruplex unwinding helicases and their function in vivo
M Sauer, K Paeschke - Biochemical Society Transactions, 2017 - portlandpress.com
The concept that G-quadruplex (G4) structures can form within DNA or RNA in vitro has
been long known and extensively discussed. In recent years, accumulating evidences imply …
been long known and extensively discussed. In recent years, accumulating evidences imply …
Transient Transcription Machineries Modulate Dynamic Functions of G‐Quadruplexes: Temporal Regulation of Biocatalytic Circuits, Gene Replication and …
Native G‐quadruplex‐regulated temporal biocatalytic circuits, gene polymerization, and
transcription processes are emulated by biomimetic, synthetically engineered transcription …
transcription processes are emulated by biomimetic, synthetically engineered transcription …
G-quadruplex structures in bacteria: biological relevance and potential as an antimicrobial target
ABSTRACT DNA strands consisting of multiple runs of guanines can adopt a noncanonical,
four-stranded DNA secondary structure known as G-quadruplex or G4 DNA. G4 DNA is …
four-stranded DNA secondary structure known as G-quadruplex or G4 DNA. G4 DNA is …
G-quadruplex structural variations in human genome associated with single-nucleotide variations and their impact on gene activity
J Gong, C Wen, M Tang, R Duan… - Proceedings of the …, 2021 - National Acad Sciences
G-quadruplexes (G4s) formed by guanine-rich nucleic acids play a role in essential
biological processes such as transcription and replication. Besides the> 1.5 million putative …
biological processes such as transcription and replication. Besides the> 1.5 million putative …
Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives
G-quadruplex structures formed by guanine-rich nucleic acids are implicated in essential
physiological and pathological processes and nanodevices. G-quadruplexes are normally …
physiological and pathological processes and nanodevices. G-quadruplexes are normally …
RNA G-quadruplex structures mediate gene regulation in bacteria
Guanine (G)-rich sequences in RNA can fold into diverse RNA G-quadruplex (rG4)
structures to mediate various biological functions and cellular processes in eukaryotic …
structures to mediate various biological functions and cellular processes in eukaryotic …