Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Distinct features of iron based metal organic frameworks (MOFs) for ferroptosis mediated cancer therapy: A comprehensive review

R Kudarha, N Dhas, S Mutalik - Coordination Chemistry Reviews, 2023 - Elsevier
In the recent years, ferroptosis, a novel non-apoptotic iron dependent form of programmed
cell death, gained lots of attention in the treatment of several disease like cancer, ischemic …

Stimuli-responsive design of metal–organic frameworks for cancer theranostics: current challenges and future perspective

J Pantwalawalkar, P Mhettar, S Nangare… - ACS Biomaterials …, 2023 - ACS Publications
Scientific fraternity revealed the potential of stimuli-responsive nanotherapeutics for cancer
treatment that aids in tackling the major restrictions of traditionally reported drug delivery …

Cellular hypoxia mitigation by dandelion-like nanoparticles for synergistic photodynamic therapy of oral squamous cell carcinoma

Y Tao, Y Liu, Z Dong, X Chen, Y Wang… - … applied materials & …, 2022 - ACS Publications
Hypoxia at the tumor site limits the therapeutic effects of photodynamic therapy (PDT) in oral
squamous cell carcinoma (OSCC), which is an oxygen-consumption process. Inhibiting …

Mitochondria Targeted O2 Economizer to Alleviate Tumor Hypoxia for Enhanced Photodynamic Therapy

P Yuan, FA Deng, YB Liu, RR Zheng… - Advanced …, 2021 - Wiley Online Library
Photodynamic therapy (PDT) often suffers from the exacerbated tumor hypoxia and the
heterogeneous distribution of photosensitizers, leading to an inefficient ROS productivity …

Ferroptosis in cancer therapeutics: a materials chemistry perspective

Q Guan, LL Zhou, YB Dong - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Ferroptosis, distinct from apoptosis, is a regulated form of cell death caused by lipid
peroxidation that has attracted extensive research interest since it was first defined in 2012 …

Rationally Integrated Precise ER‐Targeted and Oxygen‐Compensated Photodynamic Immunostimulant for Immunogenicity‐Boosted Tumor Therapy

Y Qian, M Wang, Y Xie, Q Sun… - Advanced Healthcare …, 2023 - Wiley Online Library
Notwithstanding that immunotherapy has made eminent clinical breakthroughs, activating
the immunogenicity and breaking the immunosuppressive tumor microenvironment (ITME) …

Synergetic lethal energy depletion initiated by cancer cell membrane camouflaged nano-inhibitor for cancer therapy

F Dong, Q Jiang, L Li, T Liu, S Zuo, L Gao, M Fang… - Nano Research, 2022 - Springer
Mitochondrial bioenergy plays a vital role in the occurrence and development of cancer.
Although strategies to impede mitochondrial energy supply have been rapidly developed …

Sequentially targeting cancer‐associated fibroblast and mitochondria alleviates tumor hypoxia and inhibits cancer metastasis by preventing “soil” formation and “seed” …

X Yi, Y Yan, L Li, Q Li, Y Xiang… - Advanced Functional …, 2021 - Wiley Online Library
Tumor metastasis is facilitated by the formation of the premetastatic niche (PMN) in
destination organs and the dissemination of cancer cells detached from a primary tumor …

Recent Advances in Tetrakis (4‐Carboxyphenyl) Porphyrin‐Based Nanocomposites for Tumor Therapy

Y Xie, M Wang, Q Sun, D Wang… - Advanced NanoBiomed …, 2023 - Wiley Online Library
Cancer has always been a terrible disease threatening human life. Although many
researches have been carried out on cancer, there is still no way to cure it. Emerging …