Abstract 17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many
tissue and organ functions in physiology. The effects of E2 on cells are mediated by the …

Phytoestrogens are plant‐derived dietary compounds with structural similarity to 17‐β‐
oestradiol (E2), the primary female sex hormone. This structural similarity to E2 enables …

Primary prevention through lifestyle interventions is a cost-effective alternative for preventing
a large burden of chronic and degenerative diseases, including cancer, which is one of the …

Current standard-of-care (SOC) therapy for breast cancer includes targeted therapies such
as endocrine therapy for estrogen receptor-alpha (ERα) positive; anti-HER2 monoclonal …

Types of Cell Culture Media Animal cells can be cultured either using a completely natural
medium or an artificial/synthetic medium along with some natural products. Natural Media …

Nowadays, diet and specific dietary supplements are seen as potential adjuvants to prevent
different chronic diseases, including cancer, or to ameliorate pharmacological therapies …

In mammals, the effects of estrogen are mainly mediated by two different estrogen receptors,
ERα and ERβ. These proteins are members of the nuclear receptor family, characterized by …

Microglia and astrocytes play essential roles in the maintenance of homeostasis within the
central nervous system, but mechanisms that control the magnitude and duration of …

The two oestrogen receptor subtypes α and β are hormone-regulated modulators of
intracellular signalling and gene expression. Regulation of oestrogen receptor activity is …

Estradiol (E2) is a major hormone controlling women fertility, in particular folliculogenesis.
This steroid, which is locally produced by granulosa cells (GC) within ovarian follicles …