HCC (hepatocellular carcinoma) is the second leading cause of cancer deaths worldwide,
with several etiologic causes, mostly inflammation-associated. Different inflammatory …

Although platelets are traditionally recognized for their central role in hemostasis, many lines
of research clearly demonstrate these rather ubiquitous blood components are potent …

The liver is the largest solid organ in the body and is critical for metabolic and immune
functions. However, little is known about the cells that make up the human liver and its …

Growing lines of evidence recognize that platelets play a central role in liver homeostasis
and pathobiology. Platelets have important roles at every stage during the continuum of liver …

Hepatocellular carcinoma (HCC) is a primary liver cancer that usually develops in the setting
of chronic inflammation and liver damage. The hepatic microenvironment plays a crucial role …

Liver fibrosis due to viral or metabolic chronic liver diseases is a major challenge of global
health. It is a critical pre-stage condition of severe hepatopathy, characterized by excessive …

Background Studies on temporal changes in noninvasive fibrosis indices and liver stiffness
measurement (LSM) in patients with chronic hepatitis C (CHC) treated with direct-acting …

Acetaminophen (APAP) is the main cause of acute liver failure in the West. Specific
efficacious therapies for acute liver failure (ALF) are limited and time-dependent. The …

Portal hypertension develops as a result of increased intrahepatic vascular resistance often
caused by chronic liver disease that leads to structural distortion by fibrosis, microvascular …

The effects of normothermic machine perfusion (NMP) on the postreperfusion
hemodynamics and extrahepatic biliary duct histology of donation after cardiac death (DCD) …