[HTML][HTML] Salmonella-mediated blood‒brain barrier penetration, tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy

Z Mi, Q Yao, Y Qi, J Zheng, J Liu, Z Liu, H Tan… - … Pharmaceutica Sinica B, 2023 - Elsevier
Chemotherapy is an important adjuvant treatment of glioma, while the efficacy is far from
satisfactory, due not only to the biological barriers of blood‒brain barrier (BBB) and blood …

Macrophage-tumor cell intertwine drives the transition into a mesenchymal-like cellular state of glioblastoma

Z Chen, D Hambardzumyan - Cancer Cell, 2021 - cell.com
Macrophages are the major non-neoplastic infiltrates in the glioblastoma microenvironment.
In this issue of Cancer Cell, Hara et al.(2021) demonstrate that macrophages induce a …