Down syndrome (DS) is the most common genetic alteration in humans, resulting from the
trisomy of chromosome 21. Individuals with DS are characterized by physical traits and …

Background Obesity is a significant risk factor for Alzheimer's disease; however, this
association has not been explored in adults with Down syndrome. Objective To examine the …

Down's syndrome (DS) is the most well-known chromosomal abnormality characterized by
an extra chromosome 21 and multiple systemic issues. The higher production of amyloid …

Introduction Evidence in the general population suggests that predictors of cardiovascular
health such as moderate to vigorous physical activity (MVPA), cardiorespiratory fitness, and …

INTRODUCTION Adults with Down syndrome (DS) have an increased risk of Alzheimer's
disease (AD) dementia, often showing neuropathological indicators by age 40. Physical …

This paper builds on the recently proposed prediction test for muliple endpoints. The
prediction test combines information across multiple endpoints while accounting for the …

Methods This cross-sectional study used baseline accelerometer data from individuals with
ID participating in clinical trials. The Troiano adult and Freedson child cut-points were used …

The lifespan of people with cognitive disabilities (ID) has increased significantly, but the
cognitive aspects together with the functional ones comparing normal aging and those with …

Alzheimer's disease (AD) affects cognition, behavior, and memory of brain. It causes 60–
80% of dementia cases. Cross-sectional imaging investigations of AD show that magnetic …

Background: Down Syndrome (DS) poses unique challenges in cognitive functioning,
characterized by deficits in language, memory, and executive functions. This review …