Connecting heart failure with preserved ejection fraction and renal dysfunction: the role of endothelial dysfunction and inflammation

JM Ter Maaten, K Damman, MC Verhaar… - European journal of …, 2016 - Wiley Online Library
Renal dysfunction in heart failure with preserved ejection fraction (HFpEF) is common and is
associated with increased mortality. Impaired renal function is also a risk factor for …

Polymorphisms of ABCC5 and NOS3 genes influence doxorubicin cardiotoxicity in survivors of childhood acute lymphoblastic leukemia

M Krajinovic, J Elbared, S Drouin, L Bertout… - The …, 2016 - nature.com
Anthracyclines are efficient chemotherapy agents. However, their use is limited by
anthracycline-induced cardiotoxicity (CT). We investigated the influence of polymorphisms in …

Characterizing cardiac involvement in chronic kidney disease using CMR—a systematic review

K Mangion, K McDowell, PB Mark… - Current cardiovascular …, 2018 - Springer
Abstract Purpose of Review The aim of the review was to identify and describe recent
advances (over the last 3 years) in cardiac magnetic resonance (CMR) imaging in patients …

[HTML][HTML] Mantis-ml: disease-agnostic gene prioritization from high-throughput genomic screens by stochastic semi-supervised learning

D Vitsios, S Petrovski - The American Journal of Human Genetics, 2020 - cell.com
Access to large-scale genomics datasets has increased the utility of hypothesis-free genome-
wide analyses. However, gene signals are often insufficiently powered to reach experiment …

Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants …

D El-Lebedy - Cardiovascular diabetology, 2018 - Springer
Background The aim of the present study was to examine the association of angiopoietin-
like proteins-8 (ANGPTL8) rs2278426, cholesteryl ester-transfer protein (CETP) rs708272 …

[HTML][HTML] Lack of endothelial nitric oxide synthase accelerates ectopic calcification in uremic mice fed an adenine and high phosphorus diet

Y Oe, S Mitsui, E Sato, N Shibata, K Kisu… - The American Journal of …, 2021 - Elsevier
Ectopic calcification is a risk of cardiovascular disease in chronic kidney disease (CKD)
patients, and impaired endothelial nitric oxide synthase (eNOS) is involved in the CKD …

Vascular function and myocardial performance indices in children born small for gestational age

MF Faienza, G Brunetti, M Delvecchio, A Zito… - Circulation …, 2016 - jstage.jst.go.jp
Background: Small-for-gestational-age (SGA) children have increased cardiovascular risk,
but the mediating factors are poorly understood. We hypothesized that birth size could affect …

Alpha globin gene copy number is associated with prevalent chronic kidney disease and incident end-stage kidney disease among black Americans

AP Ruhl, N Jeffries, Y Yang, RP Naik… - Journal of the …, 2022 - journals.lww.com
Background α-Globin is expressed in endothelial cells of resistance arteries, where it limits
endothelial nitric oxide signaling and enhances α-adrenergic–mediated vasoconstriction. α …

Matrix Gla Protein and Nitric Oxide Synthase‐3 Genetic Variants in Chronic Kidney Disease and Their Relation with Cardiovascular Risk

G Priyadarshini, S Parameswaran… - International Journal …, 2024 - Wiley Online Library
Background. Chronic kidney disease (CKD) is defined by gradual deterioration of renal
parenchyma and decline of functioning nephrons. The risk of cardiovascular events is …

Stochastic semi-supervised learning to prioritise genes from high-throughput genomic screens

D Vitsios, S Petrovski - bioRxiv, 2019 - biorxiv.org
Access to large-scale genomics datasets has increased the utility of hypothesis-free genome-
wide analyses that result in candidate lists of genes. Often these analyses highlight several …