G Schett, P Rahman, C Ritchlin, IB McInnes… - Nature Reviews …, 2022 - nature.com
Psoriatic arthritis (PsA) is part of a group of closely related clinical phenotypes ('psoriatic disease') that is defined by shared molecular pathogenesis resulting in excessive …
NJ Korman - British Journal of Dermatology, 2020 - academic.oup.com
Background Psoriasis is a chronic, systemic immune‐mediated disease characterized by development of erythematous, indurated, scaly, pruritic and often painful skin plaques …
J Takeshita, S Grewal, SM Langan, NN Mehta… - Journal of the American …, 2017 - Elsevier
Psoriasis is a common chronic inflammatory disease of the skin that is increasingly being recognized as a systemic inflammatory disorder. Psoriatic arthritis is a well-known …
WH Boehncke - Frontiers in immunology, 2018 - frontiersin.org
Psoriasis is a common inflammatory skin disease characterized by the appearance of red scaly plaques that can affect any part of the body. High prevalence, chronicity, disfiguration …
H Yeung, J Takeshita, NN Mehta, SE Kimmel… - JAMA …, 2013 - jamanetwork.com
Importance Despite the growing literature on comorbidity risks in psoriasis, there remains a critical knowledge gap on the degree to which objectively measured psoriasis severity may …
JJ Wu, A Kavanaugh, MG Lebwohl… - Journal of the …, 2022 - Wiley Online Library
Psoriasis is a chronic systemic inflammatory disorder associated with several comorbidities in addition to the characteristic skin lesions. Metabolic syndrome (MetS) is the most frequent …
E von Stebut, K Reich, D Thaçi, W Koenig… - Journal of Investigative …, 2019 - Elsevier
Psoriasis increases the risk of cardiovascular (CV) disease. Secukinumab, a fully human monoclonal antibody against IL-17A, shows significant efficacy in psoriasis, but effects on …
MA Lowes, CB Russell, DA Martin, JE Towne… - Trends in …, 2013 - cell.com
Psoriasis is a complex inflammatory process resulting from activation of the well-defined interleukin (IL)-23/T17 cytokine axis. We review the role of key cytokines IL-17 and IL-23 in …
SCS Hu, CCE Lan - International journal of molecular sciences, 2017 - mdpi.com
Psoriasis is a common and chronic inflammatory disease of the skin. It may impair the physical and psychosocial function of patients and lead to decreased quality of life …