Recent advances have led to the emergence of highly comprehensive and analytical
approaches, such as omics analysis and high-resolution, time-resolved bioimaging analysis …

Detailed studies of the embryo allow an increasingly mechanistic understanding of
development, which has proved of profound relevance to human disease. The last decade …

Our understanding of inherited retinal disease has benefited immensely from molecular
genetic analysis over the past several decades. New technologies that allow for increasingly …

Morphogenesis during human development relies on the interplay between physiochemical
cues that are mediated in part by cellular density and cytoskeletal tension. Here, we …

Simple Summary Microscopy is central to many areas of biomedical science research,
including cancer research, and is critical for understanding basic pathophysiology …

Human induced pluripotent stem cells (hiPSCs) are capable of differentiating into a variety of
human tissue cells. They offer new opportunities for personalized medicine and drug …

Pluripotent stem cells (PSCs) have various degrees of pluripotency, which necessitates
selection of PSCs with high pluripotency before their application to regenerative medicine …

Culturing pluripotent stem cells effectively requires substrates coated with feeder cell layers
or cell-adhesive matrices. It is difficult to employ pluripotent stem cells as resources for …

Measuring the catalytic activity of immobilized enzymes underpins development of
biosensing, bioprocessing, and analytical chemistry tools. To expand the range of …

Embryonic diapause is a conserved reproductive strategy in which development arrests at
the blastocyst phase. Recently mammalian target of rapamycin (mTOR) inhibition was …