Dendritic cell-based immunotherapy

RL Sabado, S Balan, N Bhardwaj - Cell research, 2017 - nature.com
Immunotherapy using dendritic cell (DC)-based vaccination is an approved approach for
harnessing the potential of a patient's own immune system to eliminate tumor cells in …

Dendritic cell-based immunotherapy: a basic review and recent advances

J Constantino, C Gomes, A Falcão, BM Neves… - Immunologic …, 2017 - Springer
Dendritic cells (DCs) are considered a very promising arm to activate the immune system in
immunotherapeutic strategies against cancer. DCs are the most powerful antigen-presenting …

Dendritic cell therapy in cancer treatment; the state-of-the-art

M Sadeghzadeh, S Bornehdeli… - Life sciences, 2020 - Elsevier
Dendritic cells (DCs) are considered as professional antigen presenting cells (APCs),
containing a variety of subsets, that can be resident in organs or migrating among the …

Engineered nucleic acids encoding a modified erythropoietin and their expression

JP Schrum, NB Afeyan, GJ Sieczkiewicz… - US Patent …, 2014 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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Terminally modified RNA

T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

J Dannull, Z Su, D Rizzieri, BK Yang… - The Journal of …, 2005 - Am Soc Clin Investig
In this study, we investigated whether elimination of CD4+/CD25+ Tregs using the
recombinant IL-2 diphtheria toxin conjugate DAB389IL-2 (also known as denileukin diftitox …

The emerging roles of human tissue kallikreins in cancer

CA Borgoño, EP Diamandis - Nature Reviews Cancer, 2004 - nature.com
Human tissue kallikreins (hKs), which are encoded by the largest contiguous cluster of
protease genes in the human genome, are secreted serine proteases with diverse …

Engineered nucleic acids and methods of use thereof

JP Schrum, S Bancel, NB Afeyan - US Patent 8,822,663, 2014 - Google Patents
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …

Modified polynucleotides for the production of biologics and proteins associated with human disease

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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Modified polynucleotides for the production of secreted proteins

T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
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