Mechanisms underlying overactive bladder and interstitial cystitis/painful bladder syndrome

L Grundy, A Caldwell, SM Brierley - Frontiers in neuroscience, 2018 - frontiersin.org
The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

Basic and clinical aspects of antimuscarinic agents used to treat overactive bladder

S Yamada, Y Ito, S Nishijima, K Kadekawa… - Pharmacology & …, 2018 - Elsevier
Antimuscarinic agents are now widely used as the pharmacological therapy for overactive
bladder (OAB) because neuronal (parasympathetic nerve) and non-neuronal acetylcholine …

Clinical guidelines for interstitial cystitis/bladder pain syndrome

Y Homma, Y Akiyama, H Tomoe… - … Journal of Urology, 2020 - Wiley Online Library
The clinical guidelines for interstitial cystitis and related symptomatic conditions were
revised by updating our previous guidelines. The current guidelines define interstitial …

Clinical guidelines for interstitial cystitis and hypersensitive bladder updated in 2015

Y Homma, T Ueda, H Tomoe, ATL Lin… - … Journal of Urology, 2016 - Wiley Online Library
Clinical guidelines for interstitial cystitis and hypersensitive bladder have been updated as
of 2015. The guidelines define interstitial cystitis by the presence of hypersensitive bladder …

Urine biomarkers in ESSIC type 2 interstitial cystitis/bladder pain syndrome and overactive bladder with developing a novel diagnostic algorithm

YH Jiang, JF Jhang, YH Hsu, HC Ho, YH Wu… - Scientific Reports, 2021 - nature.com
This study aimed to investigate the diagnostic values of urine cytokines in interstitial
cystitis/bladder pain syndrome (IC/BPS) and overactive bladder (OAB) patients, and to …

Urine cytokines as biomarkers for diagnosing interstitial cystitis/bladder pain syndrome and mapping its clinical characteristics

YH Jiang, JF Jhang, YH Hsu, HC Ho… - American Journal of …, 2020 - journals.physiology.org
The objective of the present study was to investigate the diagnostic values of urine cytokines
in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) and to identify their …

Urinary biomarkers in interstitial cystitis/bladder pain syndrome and its impact on therapeutic outcome

HY Lin, JH Lu, SM Chuang, KS Chueh, TJ Juan, YC Liu… - Diagnostics, 2021 - mdpi.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is defined as a chronic bladder disorder
with suprapubic pain (pelvic pain) and pressure and/or discomfort related to bladder filling …

Cross-organ sensitization between the colon and bladder: to pee or not to pee?

L Grundy, SM Brierley - American Journal of Physiology …, 2018 - journals.physiology.org
Chronic abdominal and pelvic pain are common debilitating clinical conditions experienced
by millions of patients around the globe. The origin of such pain commonly arises from the …

The effect of chronic psychological stress on lower urinary tract function: an animal model perspective

Y Gao, LV Rodríguez - Frontiers in Physiology, 2022 - frontiersin.org
Chronic psychological stress can affect urinary function and exacerbate lower urinary tract
(LUT) dysfunction (LUTD), particularly in patients with overactive bladder (OAB) or interstitial …

Feline idiopathic cystitis: pathogenesis, histopathology and comparative potential

E Jones, C Palmieri, M Thompson, K Jackson… - Journal of comparative …, 2021 - Elsevier
Bladder pain syndrome (BPS) is a debilitating disease in humans, particularly women, with
patients experiencing chronic, intractable, lower urinary and pelvic pain. Although rodent …