A critical review of recent knowledge of alcohol's effects on the immunological response in different tissues

K Crotty, P Anton, LG Coleman… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Alcohol misuse contributes to the dysregulation of immune responses and multiorgan
dysfunction across various tissues, which are associated with higher risk of morbidity and …

Regional specialization within the mammalian respiratory immune system

DPH van Konijnenburg, PA Nigrovic, I Zanoni - Trends in Immunology, 2024 - cell.com
The respiratory tract is exposed to infection from inhaled pathogens, including viruses,
bacteria, and fungi. So far, a comprehensive assessment that integrates common and …

Lack of evidence for increased transcriptional noise in aged tissues

O Ibáñez-Solé, AM Ascensión, MJ Araúzo-Bravo… - Elife, 2022 - elifesciences.org
Aging is often associated with a loss of cell type identity that results in an increase in
transcriptional noise in aged tissues. If this phenomenon reflects a fundamental property of …

Helicobacter pylori infection in infant rhesus macaque monkeys is associated with an altered lung and oral microbiome

NA Siegel, MT Jimenez, CS Rocha, M Rolston… - Scientific Reports, 2024 - nature.com
It is estimated that more than half of the world population has been infected with
Helicobacter pylori. Most newly acquired H. pylori infections occur in children before 10 …

Taxonomic and functional shifts in the perinatal gut microbiome of rhesus macaques

NS Rhoades, IR Cinco, SM Hendrickson… - Microbiology …, 2022 - Am Soc Microbiol
Pregnancy and the postpartum period result in some of the most dramatic metabolic,
hormonal, and physiological changes that can be experienced by an otherwise healthy …

Immunological and microbial shifts in the aging rhesus macaque lung during nontuberculous mycobacterial infection

IR Cinco, EG Napier, NS Rhoades, MH Davies… - Mbio, 2024 - Am Soc Microbiol
Nontuberculous mycobacteria (NTM) are environmentally ubiquitous organisms that
predominately cause NTM pulmonary disease (NTMPD) in individuals over the age of 65 …

Nasal CPAP increases alveolar number in a rhesus monkey model of moderate prematurity

CT McEvoy, KD MacDonald… - European …, 2025 - publications.ersnet.org
Rationale Most premature human infants are born in the moderate to late preterm (MLP)
range,≥ 30 to< 37 weeks gestation and demonstrate increased incidence of wheeze and …

Multi-Omics Analysis Reveals Age-Related Microbial and Metabolite Alterations in Non-Human Primates

X Chen, Y Liu, J Pu, S Gui, D Wang, X Zhong, W Tao… - Microorganisms, 2023 - mdpi.com
Aging is a systemic physiological degenerative process, with alterations in gut microbiota
and host metabolism. However, due to the interference of multiple confounding factors …

The Oral–Lung Microbiome Axis in Connective Tissue Disease-Related Interstitial Lung Disease

KS Bongers, A Massett… - Seminars in Respiratory …, 2024 - thieme-connect.com
Connective tissue disease-related interstitial lung disease (CTD-ILD) is a frequent and
serious complication of CTD, leading to high morbidity and mortality. Unfortunately, its …

Impact of aging on the immunological and microbial landscape of the lung during non-tuberculous mycobacterial infection

IR Cinco, NS Rhoades, EG Napier, M Davies… - bioRxiv, 2023 - biorxiv.org
Nontuberculous mycobacteria (NTM) are environmentally ubiquitous and predominately
cause pulmonary disease (NTMPD). The incidence of NTMPD has steadily increased and is …