Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review
K Dąbrowska - Medicinal research reviews, 2019 - Wiley Online Library
Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …
Bacteriophages in natural and artificial environments
S Batinovic, F Wassef, SA Knowler, DTF Rice… - Pathogens, 2019 - mdpi.com
Bacteriophages (phages) are biological entities that have attracted a great deal of attention
in recent years. They have been reported as the most abundant biological entities on the …
in recent years. They have been reported as the most abundant biological entities on the …
Bacteriophage transcytosis provides a mechanism to cross epithelial cell layers
Bacterial viruses are among the most numerous biological entities within the human body.
These viruses are found within regions of the body that have conventionally been …
These viruses are found within regions of the body that have conventionally been …
Intranasal delivery of biologics to the central nervous system
JJ Lochhead, RG Thorne - Advanced drug delivery reviews, 2012 - Elsevier
Treatment of central nervous system (CNS) diseases is very difficult due to the blood–brain
barrier's (BBB) ability to severely restrict entry of all but small, non-polar compounds …
barrier's (BBB) ability to severely restrict entry of all but small, non-polar compounds …
Surface-modified nanocarriers for nose-to-brain delivery: from bioadhesion to targeting
In the field of nasal drug delivery, nose-to-brain delivery is among the most fascinating
applications, directly targeting the central nervous system, bypassing the blood brain barrier …
applications, directly targeting the central nervous system, bypassing the blood brain barrier …
The influence of external factors on bacteriophages
E Jończyk, M Kłak, R Międzybrodzki, A Górski - Folia microbiologica, 2011 - Springer
The ability of bacteriophages to survive under unfavorable conditions is highly diversified.
We summarize the influence of different external physical and chemical factors, such as …
We summarize the influence of different external physical and chemical factors, such as …
Engineered bacteriophage therapeutics: rationale, challenges and future
M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …
Using graphene oxide high near-infrared absorbance for photothermal treatment of Alzheimer's disease.
A novel strategy to dissociate amyloid aggregation is presented, using localised heat
generation from a clinically used amyloid staining dye, thioflavin-S (ThS)-modified graphene …
generation from a clinically used amyloid staining dye, thioflavin-S (ThS)-modified graphene …
Genetically engineered phages: a review of advances over the last decade
Soon after their discovery in the early 20th century, bacteriophages were recognized to have
great potential as antimicrobial agents, a potential that has yet to be fully realized. The …
great potential as antimicrobial agents, a potential that has yet to be fully realized. The …
Pharmacologically aware phage therapy: pharmacodynamic and pharmacokinetic obstacles to phage antibacterial action in animal and human bodies
K Dąbrowska, ST Abedon - Microbiology and Molecular Biology …, 2019 - Am Soc Microbiol
The use of viruses infecting bacteria (bacteriophages or phages) to treat bacterial infections
has been ongoing clinically for approximately 100 years. Despite that long history, the …
has been ongoing clinically for approximately 100 years. Despite that long history, the …