[HTML][HTML] Aging, circadian disruption and neurodegeneration: Interesting interplay

AK Verma, S Singh, SI Rizvi - Experimental Gerontology, 2023 - Elsevier
The circadian system is an intricate molecular network of coordinating circadian clocks that
organize the internal synchrony of the organism in response to the environment. These …

Trichloroethylene exposure, multi-organ injury, and potential mechanisms: A narrative review

L Zhu, X Jia, H Xie, J Zhang, Q Zhu - Science of The Total Environment, 2024 - Elsevier
Trichloroethylene (TCE) is a common environmental pollutant and industrial chemical that
has been associated with adverse health effects, especially on organ systems. The purpose …

Utility of melatonin in mitigating ionizing radiation-induced testis injury through synergistic interdependence of its biological properties

ME Amer, AI Othman, HM Abozaid, MA El-Missiry - Biological Research, 2022 - Springer
Background Ionizing radiations (IR) have widespread useful applications in our daily life;
however, they have unfavorable effects on reproductive health. Maintaining testicular health …

[HTML][HTML] Hazards of trichloroethylene on the liver in animals: A systematic review and meta-analysis

H Lou, J Yang, Q Liu, Q Yang - Emerging Contaminants, 2024 - Elsevier
A systematic review and meta-analysis were conducted, aiming to establish a scientifically
grounded understanding of trichloroethylene (TCE)-induced hepatotoxicity. Relevant studies …

Crocin treatment exerts anti-inflammatory and anti-oxidative effects in liver tissue damage of pinealectomized diabetic rats

M Karayakali, E Altinoz, H Elbe, O Koca… - … Science and Pollution …, 2023 - Springer
Diabetes mellitus (DM) is a chronic metabolic disorder with an increasing global prevalence
that leads to significant morbidity and mortality. The liver plays a vital role in glycemic …

Unveiling the Protective Role of Melatonin in Osteosarcoma: Current Knowledge and Limitations

N Al-Ansari, SM Samuel, D Büsselberg - Biomolecules, 2024 - mdpi.com
Melatonin, an endogenous neurohormone produced by the pineal gland, has received
increased interest due to its potential anti-cancer properties. Apart from its well-known role in …

Circadian Clock Gene bmal1 Acts as a Tumor Suppressor Gene in a Mice Model of Human Glioblastoma

LL Trebucq, N Salvatore, PM Wagner… - Molecular …, 2024 - Springer
Glioblastomas derived from malignant astrocytes are the most common primary tumors of
the central nervous system in humans, exhibiting very bad prognosis. Treatment with …

氧化应激在三氯乙烯所致毒性效应中的作用

赵金枫, 颜士玉, 王瑞, 韩雨晴, 盘瑶 - 环境与职业医学, 2023 - jeom.org
三氯乙烯(TCE) 是常见的工业有机溶剂和环境污染物, 可通过职业接触和环境污染等途径进入
人体, 对人类健康产生严重危害. 大量研究表明氧化应激在TCE 导致的多靶器官的毒效应中发挥 …

[HTML][HTML] Granulysin-mediated reduction of PDZRN3 induces Cx43 gap junctions activity exacerbating skin damage in trichloroethylene hypersensitivity syndrome

B Jiao, H Zhang, H Jiang, S Liu, Y Wang… - Ecotoxicology and …, 2024 - Elsevier
Trichloroethylene (TCE)-induced hypersensitivity syndrome (THS) has been a concern for
many researchers in the field of environmental and occupational health. Currently, there is …

SET-mediated epigenetic dysregulation of p53 impairs trichloroethylene-induced DNA damage response

J Ruan, X Lan, S Yang, D Wu, X Huang, H Zhang, J Liu… - Toxicology Letters, 2023 - Elsevier
Trichloroethylene (TCE) was a widely used industrial solvent, and now has become a major
environmental pollutant. Exposure to TCE has been found to result in significant damage to …