Vitamin D in inflammatory diseases

TK Wöbke, BL Sorg, D Steinhilber - Frontiers in physiology, 2014 - frontiersin.org
Changes in vitamin D serum levels have been associated with inflammatory diseases, such
as inflammatory bowel disease (IBD), rheumatoid arthritis, systemic lupus erythematosus …

[HTML][HTML] Wnt/β-catenin signaling and kidney fibrosis

RJ Tan, D Zhou, L Zhou, Y Liu - Kidney international supplements, 2014 - Elsevier
Wnt/β-catenin signaling is an evolutionarily conserved, highly complex, key developmental
pathway that regulates cell fate, organ development, tissue homeostasis, as well as injury …

Pirfenidone and vitamin D mitigate renal fibrosis induced by doxorubicin in mice with Ehrlich solid tumor

RM Hazem, SA Antar, YK Nafea, AA Al-Karmalawy… - Life Sciences, 2022 - Elsevier
Aims Doxorubicin is a prominent anticancer agent. However, its organotoxic potential has
restricted its clinical use. The current study was performed to investigate the protective effect …

Vitamin D receptor: a novel therapeutic target for kidney diseases

S Yang, A Li, JW Wang, J Liu, Y Han… - Current Medicinal …, 2018 - ingentaconnect.com
Background: Kidney disease is a serious problem that adversely affects human health, but
critical knowledge is lacking on how to effectively treat established chronic kidney disease …

[HTML][HTML] Vitamin D and chronic kidney disease

CS Kim, SW Kim - The Korean journal of internal medicine, 2014 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) has been recognized as a significant global health problem
because of the increased risk of total and cardiovascular morbidity and mortality. Vitamin D …

[HTML][HTML] The role of heredity in pterygium development

P Anguria, J Kitinya, S Ntuli… - International journal of …, 2014 - ncbi.nlm.nih.gov
Several risk factors, which include heredity, ultra-violet (UV) light and chronic inflammation,
contribute to pterygium development. However, there is no report integrating these factors in …

Vitamin D and the epithelial to mesenchymal transition

MJ Larriba, A García de Herreros… - Stem cells …, 2016 - Wiley Online Library
Several studies support reciprocal regulation between the active vitamin D derivative 1α, 25‐
dihydroxyvitamin D3 (1, 25 (OH) 2D3) and the epithelial to mesenchymal transition (EMT) …

Hydrogen sulfide inhibits transforming growth factor-β1-induced EMT via Wnt/catenin pathway

L Guo, W Peng, J Tao, Z Lan, H Hei, L Tian, W Pan… - PloS one, 2016 - journals.plos.org
Hydrogen sulfide (H2S) has anti-fibrotic potential in lung, kidney and other organs. The
exogenous H2S is released from sodium hydrosulfide (NaHS) and can influence the renal …

Angiotensin-(1-7) attenuates kidney injury due to obstructive nephropathy in rats

CS Kim, IJ Kim, EH Bae, SK Ma, JU Lee, SW Kim - PloS one, 2015 - journals.plos.org
Background Angiotensin-(1–7)[Ang-(1–7)] counteracts many actions of the renin-
angiotensin-aldosterone system. Despite its renoprotective effects, extensive controversy …

Vitamin D and chronic kidney disease: Insights on lipid metabolism of tubular epithelial cell and macrophages in tubulointerstitial fibrosis

LED Gonçalves, M Andrade-Silva, PJ Basso… - Frontiers in …, 2023 - frontiersin.org
Chronic kidney disease (CKD) has been recognized as a significant global health problem
due to being an important contributor to morbidity and mortality. Inflammation is the critical …