Objective To update evidence‐based medicine recommendations for treating nonmotor
symptoms in Parkinson's disease (PD). Background The International Parkinson and …

Objectives The current guidelines aim to evaluate the role of pharmacological agents in the
treatment of patients with compulsive sexual behaviour disorder (CSBD). They are intended …

Crocus sativus L.(Saffron) has long been known for multiple target therapeutic uses. The
plant metabolism is well investigated and the main metabolites related to saffron …

Phosphodiesterases (PDEs) consisted of 11 subtypes (PDE1 to PDE11) and over 40
isoforms that regulate levels of cyclic guanosine monophosphate (cGMP) and cyclic …

Stem cell-derived exosomes (SC-EXO) was an emerging therapeutic agent in regenerative
medicine. Intratunical injection of SC-EXO is considered as a prospective approach for …

Objectives: The primary aim of these guidelines is to evaluate the role of pharmacological
agents in the treatment and management of patients with paraphilic disorders, with a focus …

Ethnopharmacological relevance The prevalence and distress caused by erectile
dysfunction (ED) to both male and female partners are increasing at a steady rate. ED has …

Sildenafil, approved two decades ago, is the inhibitor of phosphodiesterase 5 (PDE5). First
of all, it was designated for angina pectoris, but soon it showed a wonderful efficacy in …

Erectile dysfunction (ED) is important to a man's well-being and health, since it not only
affects the individual but also causes strain on a couple's lifestyle and relationship. There …

Besides pumping, the heart participates in hydro-sodium homeostasis and systemic blood
pressure regulation through its endocrine function mainly represented by the large family of …