Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology
The nematode Caenorhabditis elegans has emerged as an important animal model in
various fields including neurobiology, developmental biology, and genetics. Characteristics …
various fields including neurobiology, developmental biology, and genetics. Characteristics …
Expansion and evolution of cell death programmes
A Degterev, J Yuan - Nature reviews Molecular cell biology, 2008 - nature.com
Cell death has historically been subdivided into regulated and unregulated mechanisms.
Apoptosis, a form of regulated cell death, reflects a cell's decision to die in response to cues …
Apoptosis, a form of regulated cell death, reflects a cell's decision to die in response to cues …
Long-term exposure to 6-PPD quinone reduces reproductive capacity by enhancing germline apoptosis associated with activation of both DNA damage and cell …
X Hua, X Feng, G Liang, J Chao, D Wang - Journal of Hazardous Materials, 2023 - Elsevier
Abstract Recently, 6-PPD quinone (6-PPDQ), a derivative of tire antioxidant 6-PPD, was
reported to have acute toxicity for organisms. However, the possible reproductive toxicity of 6 …
reported to have acute toxicity for organisms. However, the possible reproductive toxicity of 6 …
Polyethylene nanoplastics cause reproductive toxicity associated with activation of both estrogenic hormone receptor NHR-14 and DNA damage checkpoints in C …
Z Liu, X Hua, Y Zhao, Q Bian, D Wang - Science of The Total Environment, 2024 - Elsevier
As the most commercial polymer, the polyethylene nanoparticle (PE-NP) has been
discharged into the environment and poses potential risks to organisms. However, the …
discharged into the environment and poses potential risks to organisms. However, the …
Paeoniflorin attenuates polystyrene nanoparticle-induced reduction in reproductive capacity and increase in germline apoptosis through suppressing DNA damage …
X Hua, X Feng, Y Hua, D Wang - Science of The Total Environment, 2023 - Elsevier
Due to high sensitivity to environmental exposures, Caenorhabditis elegans is helpful for
toxicity evaluation and toxicological study of pollutants. Using this animal model, we …
toxicity evaluation and toxicological study of pollutants. Using this animal model, we …
Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis
M Fendrych, T Van Hautegem, M Van Durme… - Current Biology, 2014 - cell.com
Background The root cap is a plant organ that ensheathes the meristematic stem cells at the
root tip. Unlike other plant organs, the root cap shows a rapid cellular turnover, balancing …
root tip. Unlike other plant organs, the root cap shows a rapid cellular turnover, balancing …
Comparison of reproductive toxicity between pristine and aged polylactic acid microplastics in Caenorhabditis elegans
Y Shao, X Hua, Y Li, D Wang - Journal of Hazardous Materials, 2024 - Elsevier
Caenorhabditis elegans was employed as model to compare reproductive toxicity between
pristine and aged polylactic acid microplastics (PLA-MPs). Aged PLA-MPs induced by UV …
pristine and aged polylactic acid microplastics (PLA-MPs). Aged PLA-MPs induced by UV …
Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG
YB Qi, EJ Garren, X Shu… - Proceedings of the …, 2012 - National Acad Sciences
We describe a method for light-inducible and tissue-selective cell ablation using a
genetically encoded photosensitizer, miniSOG (mini singlet oxygen generator). miniSOG is a …
genetically encoded photosensitizer, miniSOG (mini singlet oxygen generator). miniSOG is a …
Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis …
Y Shao, Y Wang, X Hua, Y Li, D Wang - Chemosphere, 2023 - Elsevier
Polylactic acid (PLA) accounts for approximately 45% of the global market of biodegradable
plastics. Using Caenorhabditis elegans as an animal model, we examined the effect of long …
plastics. Using Caenorhabditis elegans as an animal model, we examined the effect of long …
Caspase-Dependent Cell Death in Drosophila
BA Hay, M Guo - Annu. Rev. Cell Dev. Biol., 2006 - annualreviews.org
Cell death plays many roles during development, in the adult, and in the genesis of many
pathological states. Much of this death is apoptotic in nature and requires the activity of …
pathological states. Much of this death is apoptotic in nature and requires the activity of …