Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription
factor that regulates cell proliferation, differentiation, apoptosis, angiogenesis, inflammation …

STAT1 and STAT3 are nuclear transcription factors that regulate genes involved in cell
cycle, cell survival and immune response. The cross-talk between these signaling pathways …

Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription
factors, responsible for regulating cellular proliferation, cellular differentiation, migration …

Prostate cancer (PCa) is a prevalent malignancy that occurs primarily in old males. Prostate
tumors in different patients manifest significant inter-patient heterogeneity with respect to …

Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …

Abstract Wnt (wingless)/β-catenin signaling is critical for tumor progression and is frequently
activated in colorectal cancer as a result of the mutation of adenomatous polyposis coli …

Epithelial–mesenchymal transition (EMT) is a cell remodeling process in which epithelial
cells undergo a reversible phenotype switch via the loss of adhesion capacity and …

The cells of the prostate gland are dependent on cell signaling pathways to regulate their
growth, maintenance and function. However, perturbations in key signaling pathways …

The signal transducer and activator of transcription (STAT) 3 governs essential functions of
epithelial and hematopoietic cells that are often dysregulated in cancer. While the role for …

The Janus-kinase (JAK) and signal transducer activator of transcription (STAT) signalling
pathways regulate gene expression and control various factors involved in normal …