The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …

Tryptophan metabolites are known to participate in the regulation of many cells of the
immune system and are involved in various immune-mediated diseases and disorders …

Early detection of prostate cancer (PC) is largely carried out using assessment of prostate-
specific antigen (PSA) level; yet it cannot reliably discriminate between benign pathologies …

Kynurenic acid (KYNA) is an endogenous tryptophan metabolite exerting neuroprotective
and anticonvulsant properties in the brain. However, its importance on the periphery is still …

Prostate cancer (PCa) diagnosis with current biomarkers is difficult and often results in
unnecessary invasive procedures as well as over-diagnosis and over-treatment, highlighting …

Biosensing and microfluidics technologies are transforming diagnostic medicine by
accurately detecting biomolecules in biological samples. Urine is a promising biological fluid …

More than one million new cases of prostate cancer (PCa) were reported worldwide in 2020,
and a significant increase of PCa incidence up to 2040 is estimated. Despite potential …

Tumors accumulate metabolites that deactivate infiltrating immune cells and polarize them
toward anti-inflammatory phenotypes. We provide a comprehensive review of the complex …

This work proposed a nanozyme-mediated cascade reaction system for ratiometric
fluorescence detection of sarcosine. H 2 O 2-sensitive MnO 2 nanosheets (MnO 2 NSs) were …

Prostate cancer is the second most common cause of cancer death among men. It is an
asymptomatic and slow growing tumour, which starts occurring in young men, but can be …