Toll‐Like Receptors in Leishmania Infections: Guardians or Promoters?

MS Faria, FCG Reis, APCA Lima - Journal of parasitology …, 2012 - Wiley Online Library
Protozoa of the genus Leishmania cause a wide variety of pathologies ranging from self‐
healing skin lesions to visceral damage, depending on the parasite species. The outcome of …

[HTML][HTML] Clinical pleiomorphism in human leishmaniases, with special mention of asymptomatic infection

AL Banuls, P Bastien, C Pomares, J Arevalo… - Clinical Microbiology …, 2011 - Elsevier
This review gives an update of current knowledge on the clinical pleiomorphism of
Leishmania, with a special emphasis on the case of asymptomatic carriage. The first part …

Association of TLR1, TLR2, TLR4, TLR6, and TIRAP polymorphisms with disease susceptibility

M Noreen, M Arshad - Immunologic Research, 2015 - Springer
Toll like receptors (TLRs) play a crucial role in regulation of innate as well as adaptive
immunity. TLRs recognize a distinct but limited repertoire of conserved microbial products …

[HTML][HTML] Human genetic polymorphism and Leishmaniasis

K Bharati - Infection, Genetics and Evolution, 2022 - Elsevier
Leishmaniasis is a disease of the subtropical and tropical spheres of the earth and has
various clinical manifestations. The different form of leishmaniasis includes cutaneous …

Prevalence and associated factors of asymptomatic leishmaniasis: a systematic review and meta-analysis

SB Mannan, H Elhadad, TTH Loc, M Sadik… - Parasitology …, 2021 - Elsevier
Asymptomatic leishmaniasis is believed to play important role in maintaining the
transmission of Leishmania spp. within endemic communities. Therefore, the efforts to …

[HTML][HTML] Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogen

C Hayashi, G Papadopoulos, CV Gudino… - The Journal of …, 2012 - journals.aai.org
Clinical and epidemiological studies have implicated chronic infections in the development
of atherosclerosis. It has been proposed that common mechanisms of signaling via TLRs …

The Role of TLR4 896 A>G and 1196 C>T in Susceptibility to Infections: A Review and Meta-Analysis of Genetic Association Studies

PD Ziakas, ML Prodromou, J El Khoury, E Zintzaras… - PloS one, 2013 - journals.plos.org
Background Toll-like receptor 4 plays a role in pathogen recognition, and common
polymorphisms may alter host susceptibility to infectious diseases. Purpose To review the …

Transcription of innate immunity genes and cytokine secretion by canine macrophages resistant or susceptible to intracellular survival of Leishmania infantum

AP Turchetti, LF da Costa, E de Lima Romão… - Veterinary Immunology …, 2015 - Elsevier
In this study we assessed the basal transcription of genes associated with innate immunity
(ie Nramp1, NOD1, NOD2, TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, and TLR9) in …

Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil

LC Castellucci, LF Almeida, SE Jamieson… - Memorias do Instituto …, 2014 - SciELO Brasil
American cutaneous leishmaniasis (ACL) is a vector-transmitted infectious disease with an
estimated 1.5 million new cases per year. In Brazil, ACL represents a significant public …

Toll-like receptors 2, 4 and 7, interferon-gamma and interleukin 10, and programmed death ligand 1 transcripts in skin from dogs of different clinical stages of …

L Ordeix, S Montserrat-Sangrà, P Martínez-Orellana… - Parasites & vectors, 2019 - Springer
Abstract Background Canine leishmaniosis (CanL) caused by Leishmania infantum can
have several dermatological manifestations. The type of immune response elicited against …