Neutrophil Extracellular Traps (NETs) and Covid-19: A new frontiers for therapeutic modality

HM Al-Kuraishy, AI Al-Gareeb, HA Al-Hussaniy… - International …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (Covid-19) is a worldwide infectious disease caused by
severe acute respiratory coronavirus 2 (SARS-CoV-2). In severe SARS-CoV-2 infection …

Antimicrobial peptides—Mechanisms of action, antimicrobial effects and clinical applications

J Talapko, T Meštrović, M Juzbašić, M Tomas, S Erić… - Antibiotics, 2022 - mdpi.com
The growing emergence of antimicrobial resistance represents a global problem that not
only influences healthcare systems but also has grave implications for political and …

Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides

X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

Maternal consumption of a fermented diet protects offspring against intestinal inflammation by regulating the gut microbiota

C Wang, S Wei, B Liu, F Wang, Z Lu, M Jin, Y Wang - Gut Microbes, 2022 - Taylor & Francis
The neonatal intestinal tract is immature and can be easily infected by pathogens causing
inflammation. Maternal diet manipulation is a promising nutritional strategy to enhance the …

[HTML][HTML] Neutrophil–epithelial crosstalk during intestinal inflammation

L Kang, X Fang, YH Song, ZX He, ZJ Wang… - Cellular and molecular …, 2022 - Elsevier
Neutrophils are the most abundant leukocyte population in the human circulatory system
and are rapidly recruited to sites of inflammation. Neutrophils play a multifaceted role in …

Molecular characterization of cathelicidin in tiger frog (Hoplobatrachus rugulosus): Antimicrobial activity and immunomodulatory activity

J Chen, YF Lin, JH Chen, X Chen, ZH Lin - Comparative Biochemistry and …, 2021 - Elsevier
Cathelicidins are an important antimicrobial peptide family and are expressed in many
different vertebrates. They play an important role in the innate immune system of the host …

[HTML][HTML] Knockdown of CXCL1 improves ACLF by reducing neutrophil recruitment to attenuate ROS production and hepatocyte apoptosis

S Tang, J Zhang, L Zhang, Y Zhao, L Xiao… - Hepatology …, 2023 - journals.lww.com
Background: Acute-on-chronic liver failure (ACLF) is an acute decompensated syndrome
based on chronic liver disease, while neutrophil recruitment is the most critical early step …

Epithelial‐immune cell crosstalk for intestinal barrier homeostasis

Y Yao, W Shang, L Bao, Z Peng… - European Journal of …, 2024 - Wiley Online Library
The intestinal barrier is mainly formed by a monolayer of epithelial cells, which forms a
physical barrier to protect the gut tissues from external insults and provides a …

Early immune innate hallmarks and microbiome changes across the gut during Escherichia coli O157: H7 infection in cattle

M Larzábal, WM Da Silva, A Multani, LE Vagnoni… - Scientific Reports, 2020 - nature.com
The zoonotic enterohemorrhagic Escherichia coli (EHEC) O157: H7 bacterium causes
diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome (HUS) in humans. Cattle are …

Cathelicidins induce toll-interacting protein synthesis to prevent apoptosis in colonic epithelium

R Holani, C Rathnayaka, GAD Blyth, A Babbar… - Journal of Innate …, 2023 - karger.com
Cathelicidin peptides secreted by leukocytes and epithelial cells are microbicidal but also
regulate pathogen sensing via toll-like receptors (TLRs) in the colon by mechanisms that are …