Adenoid cystic carcinoma: a review of clinical features, treatment targets and advances in improving the immune response to monoclonal antibody therapy

J Nightingale, B Lum, R Ladwa, F Simpson… - … et Biophysica Acta (BBA …, 2021 - Elsevier
The natural history of adenoid cystic carcinoma (ACC) is relentless, defined by treatment
failure heralded by locoregional recurrence and distant metastatic disease. In this review …

Nanofibrous drug delivery systems for breast cancer: a review

T Hussain, S Ramakrishna, S Abid - Nanotechnology, 2021 - iopscience.iop.org
Breast cancer is the most common type of cancer among women. Breast-conserving surgery
(BCS) is one of the preferred approaches for treating non-invasive or early-stage breast …

The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis

C Zhao, X Ling, Y Xia, B Yan, Q Guan - Cancer Cell International, 2021 - Springer
Background Previous studies have revealed the key functions of N6-methyladenosine (m6A)
modification in breast cancer (BC). MALAT1 as a highly m6A modified lncRNA associated …

Diltiazem potentiates the cytotoxicity of gemcitabine and 5-fluorouracil in PANC-1 human pancreatic cancer cells through inhibition of P-glycoprotein

HA El-Mahdy, AA El-Husseiny, YI Kandil, AMG El-Din - Life sciences, 2020 - Elsevier
Aim Pancreatic cancer (PC) is one of the most aggressive tumors with dismal survival and a
high death rate due to chemotherapeutic failure. P-glycoprotein (P-gp) plays a pivotal role in …

Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway

W Shi, L Men, X Pi, T Jiang… - International …, 2021 - spandidos-publications.com
Signal transducer and activator of transcription 3 (STAT3) activation is associated with drug
resistance induced by anti‑epidermal growth factor receptor (anti‑EGFR) therapy in the …

Circ0120816 acts as an oncogene of esophageal squamous cell carcinoma by inhibiting miR-1305 and releasing TXNRD1

X Li, L Song, B Wang, C Tao, L Shi, M Xu - Cancer cell international, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) have been discovered to participate in the
carcinogenesis of multiple cancers. However, the role of circRNAs in esophageal squamous …

Causal meta-analysis by integrating multiple observational studies with multivariate outcomes

S Guha, Y Li - Biometrics, 2024 - academic.oup.com
Integrating multiple observational studies to make unconfounded causal or descriptive
comparisons of group potential outcomes in a large natural population is challenging …

[HTML][HTML] Patient-derived tumor organoids: A preclinical platform for personalized cancer therapy

S Taurin, R Alzahrani, S Aloraibi, L Ashi, R Alharmi… - Translational …, 2025 - Elsevier
Patient-derived tumor organoids (PDTOs) represent a significant advancement in cancer
research and personalized medicine. These organoids, derived from various cancer types …

Yin Yang 1-stimulated long noncoding RNA bladder cancer-associated transcript 1 upregulation facilitates esophageal carcinoma progression via the microRNA-5590 …

J Cheng, Q Yang, X Han, H Wang, K Wu, H Zhao - Bioengineered, 2022 - Taylor & Francis
Esophageal carcinoma (EC) is a common gastrointestinal malignancy that poses a threat to
public health worldwide. Long noncoding RNA (lncRNA) bladder cancer-associated …

[HTML][HTML] The antimalarial drug pyronaridine inhibits topoisomerase II in breast cancer cells and hinders tumor progression in vivo

PJ Villanueva, DA Gutierrez, L Contreras… - Clinical cancer …, 2021 - ncbi.nlm.nih.gov
Background: Breast cancer is the most frequently diagnosed cancer in women worldwide.
Pyronaridine (PND), an antimalarial drug, was shown to exert anticancer activity on …