Design and hybridization properties of acyclic xeno nucleic acid oligomers
K Murayama, H Asanuma - ChemBioChem, 2021 - Wiley Online Library
Xeno nucleic acids (XNAs) are analogues of DNA and RNA that have a non‐ribose artificial
scaffold. XNAs are possible prebiotic genetic carriers as well as alternative genetic systems …
scaffold. XNAs are possible prebiotic genetic carriers as well as alternative genetic systems …
Recent advances in nucleic acid targeting probes and supramolecular constructs based on pyrene-modified oligonucleotides
In this review, we summarize the recent advances in the use of pyrene-modified
oligonucleotides as a platform for functional nucleic acid-based constructs. Pyrene is of …
oligonucleotides as a platform for functional nucleic acid-based constructs. Pyrene is of …
Integration of G-Quadruplex and Pyrene as a Simple and Efficient Ratiometric Fluorescent Platform That Programmed by Contrary Logic Pair for Highly Sensitive and …
J Han, Y Ding, X Lv, Y Zhang, D Fan - Biosensors, 2023 - mdpi.com
The effective and accurate detection of the anticancer drug coralyne (COR) is highly
significant for drug quality control, medication safety and good health. Although various COR …
significant for drug quality control, medication safety and good health. Although various COR …
Acyclic Nucleic Acids with Phosphodiester Linkages—Synthesis, Properties and Potential Applications
A Tomaszewska-Antczak, P Guga - Applied Sciences, 2021 - mdpi.com
This review summarizes the synthetic efforts on acyclic analogs of nucleic acids and
provides information on the most interesting features of selected classes of such …
provides information on the most interesting features of selected classes of such …
Carbazole modified oligonucleotides: synthesis, hybridization studies and fluorescence properties
Synthesis of the novel thiophenyl carbazole phosphoramidite DNA building block 5 was
accomplished in four steps using a Suzuki–Miyaura cross-coupling reaction from the core …
accomplished in four steps using a Suzuki–Miyaura cross-coupling reaction from the core …
3′-Pyrene-modified unlocked nucleic acids: synthesis, fluorescence properties and a surprising stabilization effect on duplexes and triplexes
M Ejlersen, N Langkjær, J Wengel - Organic & Biomolecular Chemistry, 2017 - pubs.rsc.org
Efficient synthesis of a new 3′-O-amino-UNA monomer was developed as a scaffold for
further functionalization and incorporation into oligonucleotides (ONs). Pyrene …
further functionalization and incorporation into oligonucleotides (ONs). Pyrene …
[HTML][HTML] An efficient green synthesis of UNA-nucleoside-5′-triphosphates: A versatile synthon for RNA modification with broad therapeutic potential
M Shanmugasundaram, A Senthilvelan, AR Kore - Results in Chemistry, 2023 - Elsevier
A facile, reliable, and an efficient “one-pot, two-step” method for the gram-scale chemical
synthesis of UNA-nucleoside-5′-triphosphate, starting from the commercially available …
synthesis of UNA-nucleoside-5′-triphosphate, starting from the commercially available …
Fluorescent Oligonucleotides with Bis (prop-2-yn-1-yloxy) butane-1, 3-diol Scaffold Rapidly Detect Disease-Associated Nucleic Acids
M Taskova, K Astakhova - Bioconjugate Chemistry, 2019 - ACS Publications
Biomedical research and clinical work demand rapid and reliable detection of disease-
associated nucleic acids. Fluorescent oligonucleotides that bind precisely, and sense target …
associated nucleic acids. Fluorescent oligonucleotides that bind precisely, and sense target …
An Efficient Gram‐Scale Chemical Synthesis of UNA‐Nucleoside‐5′‐O‐Triphosphates
A Senthilvelan, M Shanmugasundaram… - Current …, 2023 - Wiley Online Library
This unit describes a facile, reliable, and efficient method for the gram‐scale chemical
synthesis of unlocked nucleic acid‐(UNA) nucleoside‐5′‐O‐triphosphates such as UNA …
synthesis of unlocked nucleic acid‐(UNA) nucleoside‐5′‐O‐triphosphates such as UNA …