Genetic testing has evolved rapidly over recent years and new developments have the
potential to provide insights that could improve the ability to diagnose, treat, and prevent …

Background: With advances in genetic and genomic medicine, the optimal integration of
genetic services into the health care system remains of major concern in many countries …

The slow rate at which pharmacogenetic tests are being adopted in clinical practice is partly
due to the lack of specific guidelines on how to adjust medications on the basis of the …

Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application
into routine care remains limited. Opportunely, several implementation studies and …

The demand to bring transformative therapeutics to patients and the escalating costs of
doing so are driving the life science industry to seek collaborations with academia to …

Introduction Aberrant pharmacogenetic variants occur in a high proportion of people and
might be relevant for the prescription of over 26 drugs in primary care. Early identification of …

Polygenic scores (PGS) are primed for use in personalized risk assessments for common,
complex conditions and population health screening. Although there is growing evidence …

Introduction: Pharmacogenomic testing can indicate which drugs may have limited
therapeutic action or lead to adverse effects, hence guiding rational and safe prescribing …

Purpose: Personalized medicine—the use of genomics and molecular diagnostics to direct
care decisions—may improve outcomes by more accurately individualizing treatment to …

Clinical next generation sequencing (NGS) is a term that refers to a variety of technologies
that permit rapid sequencing of large numbers of DNA segments, up to and including entire …