The role of prolactin in central nervous system inflammation

E Ramos-Martinez, I Ramos-Martínez… - Reviews in the …, 2021 - degruyter.com
Prolactin has been shown to favor both the activation and suppression of the microglia and
astrocytes, as well as the release of inflammatory and anti-inflammatory cytokines. Prolactin …

Research progress on the role of hormones in ischemic stroke

S Huang, L Liu, X Tang, S Xie, X Li, X Kang… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke is a major cause of death and disability around the world. However,
ischemic stroke treatment is currently limited, with a narrow therapeutic window and …

Risperidone ameliorated 1, 2-Diacetylbenzene-induced cognitive impairments in mice via activating prolactin signaling pathways

HD Nguyen, WH Jo, NHM Hoang, MS Kim - International …, 2023 - Elsevier
Cognitive impairment and organic solvent exposure have been becoming public health
concerns due to an increasingly aging population, increased life expectancy, urbanization …

Decoding signaling pathways involved in prolactin-induced neuroprotection: A review

G Molina-Salinas, NA Rivero-Segura… - Frontiers in …, 2021 - Elsevier
It has been well recognized that prolactin (PRL), a pleiotropic hormone, has many functions
in the brain, such as maternal behavior, neurogenesis, and neuronal plasticity, among …

High-dose vitamin C prevents secondary brain damage after stroke via epigenetic reprogramming of neuroprotective genes

KC Morris-Blanco, AK Chokkalla, TH Kim… - Translational stroke …, 2022 - Springer
Vitamin C has recently been identified as an epigenetic regulator by activating ten-eleven
translocases (TETs), enzymes involved in generating DNA hydroxymethylcytosine (5hmC) …

Neuroendocrine regulation in stroke

A Datta, C Saha, P Godse, M Sharma, D Sarmah… - Trends in Endocrinology …, 2023 - cell.com
The neuroendocrine system, a crosstalk between the central nervous system and endocrine
glands, balances and controls hormone secretion and their functions. Neuroendocrine …

Neuroprotection mediated by prolactin against streptozotocin injury in brain rat areas

E Ramos-Martínez, EKP Almeida-Aguirre… - Brain Research, 2024 - Elsevier
Prolactin has been recognized as neuroprotective hormone against various types of
neuronal damage. This study was aimed to determine if prolactin protects against …

Traumatic brain injury and prolactin

A Hacioglu, F Tanriverdi - Reviews in Endocrine and Metabolic Disorders, 2024 - Springer
Traumatic brain injury (TBI) is a well-known etiologic factor for pituitary dysfunctions, with a
prevalence of 15% during long-term follow-up. The most common hormonal disruption is …

Prolactin neuroprotective action against excitotoxic insult in the hippocampus of male mice

I Anagnostou, D Muñoz-Mayorga, T Morales - Peptides, 2021 - Elsevier
Prolactin (PRL) is known to exert neuroprotective effects against excitotoxic damage in the
hippocampus of female rats, both in vitro and in vivo. It is still unknown whether this effect …

The brain as a source and a target of prolactin in mammals

AR Costa-Brito, I Gonçalves… - Neural Regeneration …, 2022 - journals.lww.com
Prolactin is a polypeptide hormone associated with an extensive variety of biological
functions. Among the roles of prolactin in vertebrates, some were preserved throughout …