Ceramides are a class of sphingolipids which are implicated in skin disorders, obesity, and
other metabolic diseases. As a class with pleiotropic effects, recent efforts have centred on …

Ceramide is a core molecule of sphingolipid metabolism that causes selective insulin
resistance and dyslipidemia. Research on its involvement in cardiovascular diseases has …

Lipidomics encompassing automated lipid extraction, a four-dimensional (4D) feature
selection strategy for confident lipid annotation as well as reproducible and cross-validated …

Palmitic acid is the predominant dietary saturated fatty acid (SFA) in the US diet. Plasma
palmitic acid is derived from dietary fat and also endogenously from de novo lipogenesis …

Background Elevated plasma ceramides are independent predictors of cardiovascular
disease and mortality in patients with advanced epicardial coronary artery disease. Our …

Background The ceramide-and phospholipid-based cardiovascular risk score (CERT2) has
been found to predict the risk for cardiovascular disease (CVD) events, especially …

Background The effects of replacing dietary saturated fatty acids (SFAs) with
monounsaturated fatty acids (MUFAs) and/or polyunsaturated fatty acids (PUFAs) on the …

Lipidomics as a branch of metabolomics provides unique information on the complex lipid
profile in biological materials. In clinically focused studies, hundreds of lipids together with …

Therapeutic approaches that lower circulating low-density lipoprotein (LDL)-cholesterol
significantly reduced the burden of cardiovascular disease over the last decades. However …

(−)-Epicatechin gallate (ECG), as a compound in green tea extract polyphenols, has specific
therapeutic effects against oxidative stress. Oxidative stress exists throughout the …