Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

Introduction It is currently admitted that adverse drug reactions (ADRs) account for a great
burden of disease. Of particular concern are ADR-induced hospital admissions, particularly …

Objectives Assess the longitudinal association between polypharmacy and falls and
examine the differences in this association by different thresholds for polypharmacy …

Chronic insomnia affects 57% of the elderly in the United States, with impairment of quality
of life, function, and health. Chronic insomnia burdens society with billions of dollars in direct …

Background Patients with chronic kidney disease (CKD) bear a substantial burden of
comorbidities leading to the prescription of multiple drugs and a risk of polypharmacy …

Polypharmacy describes, in simplistic terms, the use of multiple medications in an individual.
It has become a normal aspect of modern medicine, driven by an ageing, multimorbid …

Background Mixed findings about deprescribing impact have emerged from varied study
designs, interventions, outcome measures and targeting sub-categories of medications or …

Background Multimorbidity and polypharmacy are very common in older adults in primary
care. Ideally, general practitioners (GPs), should regularly review medication lists to identify …

Background Non-optimal medication use among older adults is a public health concern. A
concrete picture of potentially inappropriate medication (PIM) use is imperative to ensure …