Bromelain a potential bioactive compound: a comprehensive overview from a pharmacological perspective

AJ Chakraborty, S Mitra, TE Tallei, AM Tareq, F Nainu… - Life, 2021 - mdpi.com
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple
stems. It contains several thiol endopeptidases and is extracted and purified via several …

Beneficial properties of bromelain

P Hikisz, J Bernasinska-Slomczewska - Nutrients, 2021 - mdpi.com
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

Bromelain, a Group of Pineapple Proteolytic Complex Enzymes (Ananas comosus) and Their Possible Therapeutic and Clinical Effects. A Summary

C Varilla, M Marcone, L Paiva, J Baptista - Foods, 2021 - mdpi.com
Bromelain is a complex combination of multiple endopeptidases of thiol and other
compounds derived from the pineapple fruit, stem and/or root. Fruit bromelain and stem …

Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases

DM Heuberger, RA Schuepbach - Thrombosis journal, 2019 - Springer
Inflammatory diseases have become increasingly prevalent with industrialization. To
address this, numerous anti-inflammatory agents and molecular targets have been …

Diabetic retinopathy, a vascular and inflammatory disease: therapeutic implications

F Semeraro, F Morescalchi, A Cancarini, A Russo… - Diabetes & …, 2019 - Elsevier
Diabetic retinopathy (DR) is the most common microvascular complication of diabetes and
the leading cause of visual impairment in the working-age population in the Western world …

Valorisation of pineapple wastes for food and therapeutic applications

S Banerjee, V Ranganathan, A Patti, A Arora - Trends in food science & …, 2018 - Elsevier
Background Fruit and vegetable processing industries account for the largest segment of
food waste which is produced worldwide. The disposal of this waste requires a huge capital …

Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

[图书][B] Surface modification of nanoparticles for targeted drug delivery

P Patel, A Hanini, A Shah, D Patel, S Patel, P Bhatt… - 2019 - Springer
Over the course of recent years, nanoparticles have been the center of attention used to treat
many health related diseases. Nanoparticles are used due to it being efficient and having …

Bromelain: A review of its mechanisms, pharmacological effects and potential applications

V Kumar, B Mangla, S Javed, W Ahsan, P Kumar… - Food & function, 2023 - pubs.rsc.org
The utilization of plant-derived supplements for disease prevention and treatment has long
been recognized because of their remarkable potential. Ananas comosus, commonly known …