The oral cavity and oropharynx are complex environments that are susceptible to physical,
chemical, and microbiological insults. They are also common sites for pathological and …

Abstract The three‐dimensional (3D) multicellular platforms prepared by cells or
biomaterials have been widely applied in biomedical fields for the regeneration of complex …

Objectives To investigate the effect of three different calcium silicate-based materials
(CSBM) on the biological behavior of human periodontal ligament stem cells (hPDLSCs) …

Background Periodontitis often causes irrevocable destruction of tooth-supporting tissues
and eventually leads to tooth loss. Currently, stem cell-based tissue engineering has …

Bone defects that are congenital or the result of infection, malignancy, or trauma represent a
challenge to the global healthcare system. To address this issue, multiple research groups …

Periodontitis, a globally prevalent chronic inflammatory disease is characterized by the
progressive degradation of tooth-supporting structures, particularly the periodontal ligament …

Different approaches to develop engineered scaffolds for periodontal tissues regeneration
have been proposed. In this review, innovations in stem cell technology and scaffolds …

In recent years, tissue engineering studies have proposed several approaches to
regenerate periodontium based on the use of three-dimensional (3D) tissue scaffolds alone …

Background Osteogenic differentiation of periodontal ligament stem cells (PDLSCs) is
associated with periodontitis. It has been reported that long noncoding RNA X-inactive …

The goal of periodontal regenerative therapy is to predictably restore the tooth's supporting
periodontal tissues and form a new connective tissue attachment of periodontal ligament …