The role of mammalian Sirtuin 6 in cardiovascular diseases and diabetes mellitus
K Wu, Y Wang, R Liu, H Wang, T Rui - Frontiers in Physiology, 2023 - frontiersin.org
Cardiovascular diseases are severe diseases posing threat to human health because of
their high morbidity and mortality worldwide. The incidence of diabetes mellitus is also …
their high morbidity and mortality worldwide. The incidence of diabetes mellitus is also …
[HTML][HTML] Unlocking the potential: caloric restriction, caloric restriction mimetics, and their impact on cancer prevention and treatment
UE De-Leon-Covarrubias, JJ Perez-Trujillo… - Metabolites, 2024 - mdpi.com
Caloric restriction (CR) and its related alternatives have been shown to be the only
interventions capable of extending lifespan and decreasing the risk of cancer, along with a …
interventions capable of extending lifespan and decreasing the risk of cancer, along with a …
Insights into the microscopic heterogeneity of whey proteins between yak colostrum and mature milk based on 4D lable-free quantitative phosphoproteomics
Y Li, X Yang, C Shi, L Wang, Y Wang, W Zhang… - Food Chemistry, 2024 - Elsevier
This study aimed to reveal the change patterns of the phosphorylation modification status of
yak whey phosphoproteins during lactation and their physiological effects. Herein, we …
yak whey phosphoproteins during lactation and their physiological effects. Herein, we …
Exploring the therapeutic potential of Sirt6-enriched adipose stem cell-derived exosomes in myocardial ischemia–reperfusion injury: unfolding new epigenetic …
K Liu, H Wang, Y Wang, X Zhang, R Wang, Z Zhang… - Clinical …, 2024 - Springer
Background The management of myocardial ischemia–reperfusion injury (MIRI) presents
continuous therapeutic challenges. NAD-dependent deacetylase Sirtuin 6 (Sirt6) plays …
continuous therapeutic challenges. NAD-dependent deacetylase Sirtuin 6 (Sirt6) plays …
SIRT6 deficiency in endothelial cells exacerbates oxidative stress by enhancing HIF1α accumulation and H3K9 acetylation at the Ero1α promoter
Z Guo, X Yu, S Zhao, X Zhong, D Huang… - Clinical and …, 2023 - Wiley Online Library
Background SIRT6, an important NAD+‐dependent protein, protects endothelial cells from
inflammatory and oxidative stress injuries. However, the role of SIRT6 in cardiac …
inflammatory and oxidative stress injuries. However, the role of SIRT6 in cardiac …
Large-scale lysine crotonylation analysis reveals the role of TRAF6-Ecsit complex in endoplasmic reticulum stress in mud crab (Scylla paramamosain)
Y Zhang, P Ji, M Zhang, NT Tran, S Li - Developmental & Comparative …, 2023 - Elsevier
Lysine crotonylation (Kcr) is a newly discovered type of post-translational modification.
Although Kcr has been reported in several species, its role in crustaceans remains largely …
Although Kcr has been reported in several species, its role in crustaceans remains largely …
Targeting endoplasmic reticulum stress‐induced lymphatic dysfunction for mitigating bisphosphonate‐related osteonecrosis
Z Qin, H Xie, P Su, Z Song, R Xu, S Guo… - Clinical and …, 2024 - Wiley Online Library
Abstract Background Bisphosphonates (BPs) are the first‐line treatment to stop bone
resorption in diseases, including osteoporosis, Paget's disease, multiple myeloma and bone …
resorption in diseases, including osteoporosis, Paget's disease, multiple myeloma and bone …