It is remarkable how robustly a bacterial species can maintain its preferred size. This
capacity is intimately related to control of the cell cycle: cell size and growth rate determine …

Most microorganisms regulate their cell size. In this article, we review some of the
mathematical formulations of the problem of cell size regulation. We focus on coarse …

Defining the cellular factors that drive growth rate and proteome composition is essential for
understanding and manipulating cellular systems. In bacteria, ribosome concentration is …

Rod-shaped bacterial cells can readily adapt their lengths and widths in response to
environmental changes. While many recent studies have focused on the mechanisms …

To maximize their fitness, cells must be able to respond effectively to stresses. This demands
making trade-offs between processes that conserve resources to promote survival, and …

In nature, microorganisms exhibit different volumes spanning six orders of magnitude.
Despite their capability to create different sizes, a clonal population in a given environment …

The growth rate of single bacterial cells is continuously disturbed by random fluctuations in
biosynthesis rates and by deterministic cell-cycle events, such as division, genome …

Cell cycle progression requires the coordination of cell growth, chromosome replication and
division. Consequently, a functional cell cycle must be coupled with metabolism. However …

Collection of high-throughput data has become prevalent in biology. Large datasets allow
the use of statistical constructs such as binning and linear regression to quantify …

Microbial growth and division are fundamental processes relevant to many areas of life
science. Of particular interest are homeostasis mechanisms, which buffer growth and …