Identification, evaluation, and management of children with autism spectrum disorder

SL Hyman, SE Levy, SM Myers, DZ Kuo, S Apkon… - …, 2020 - publications.aap.org
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder with reported
prevalence in the United States of 1 in 59 children (approximately 1.7%). Core deficits are …

Selection bias on intellectual ability in autism research: A cross-sectional review and meta-analysis

G Russell, W Mandy, D Elliott, R White, T Pittwood… - Molecular autism, 2019 - Springer
Background Current global estimates suggest the proportion of the population with autism
spectrum disorder (ASD) who have intellectual disability (ID) is approximately 50%. Our …

Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours

B Lee, K Lee, S Panda, R Gonzales-Rojas… - Nature biomedical …, 2018 - nature.com
Technologies that can safely edit genes in the brains of adult animals may revolutionize the
treatment of neurological diseases and the understanding of brain function. Here, we …

Premature mortality in autism spectrum disorder

T Hirvikoski, E Mittendorfer-Rutz, M Boman… - The British Journal of …, 2016 - cambridge.org
BackgroundMortality has been suggested to be increased in autism spectrum disorder
(ASD). AimsTo examine both all-cause and cause-specific mortality in ASD, as well as …

Glycogen synthase kinase-3 inhibitors: preclinical and clinical focus on CNS-A decade onward

SM Arciniegas Ruiz, H Eldar-Finkelman - Frontiers in molecular …, 2022 - frontiersin.org
The protein kinase, GSK-3, participates in diverse biological processes and is now
recognized a promising drug discovery target in treating multiple pathological conditions …

Global processing takes time: A meta-analysis on local–global visual processing in ASD.

R Van der Hallen, K Evers, K Brewaeys… - Psychological …, 2015 - psycnet.apa.org
What does an individual with autism spectrum disorder (ASD) perceive first: the forest or the
trees? In spite of 30 years of research and influential theories like the weak central …

Autistic spectrum disorders: A review of clinical features, theories and diagnosis

M Fakhoury - International journal of developmental neuroscience, 2015 - Elsevier
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders that is among the
most severe in terms of prevalence, morbidity and impact to the society. It is characterized by …

Reelin functions, mechanisms of action and signaling pathways during brain development and maturation

Y Jossin - Biomolecules, 2020 - mdpi.com
During embryonic development and adulthood, Reelin exerts several important functions in
the brain including the regulation of neuronal migration, dendritic growth and branching …

Urinary metabolomics of young Italian autistic children supports abnormal tryptophan and purine metabolism

F Gevi, L Zolla, S Gabriele, AM Persico - Molecular autism, 2016 - Springer
Background Autism spectrum disorder (ASD) is still diagnosed through behavioral
observation, due to a lack of laboratory biomarkers, which could greatly aid clinicians in …

Neuropsychopathology of autism spectrum disorder: complex interplay of genetic, epigenetic, and environmental factors

R Bhandari, JK Paliwal, A Kuhad - … food intervention and therapy for autism …, 2020 - Springer
Autism spectrum disorder (ASD) is a complex heterogeneous consortium of pervasive
development disorders (PDD) which ranges from atypical autism, autism, and Asperger …