Risk of colorectal cancer in inflammatory bowel diseases

MS Nadeem, V Kumar, FA Al-Abbasi, MA Kamal… - Seminars in cancer …, 2020 - Elsevier
Inflammatory bowel diseases (IBDs) are chronic problems of gastrointestinal tract (GIT) with
poorly understood aetiology. Patients with any of the two common entities, Crohn's disease …

Looking at NSAIDs from a historical perspective and their current status in drug repurposing for cancer treatment and prevention

A Ozleyen, YB Yilmaz, S Donmez, HN Atalay… - Journal of Cancer …, 2023 - Springer
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most frequently prescribed
drug classes with wide therapeutic applications over the centuries. Starting from the use of …

The relatively selective cyclooxygenase-2 inhibitor nimesulide: What's going on?

E Caiazzo, A Ialenti, C Cicala - European Journal of Pharmacology, 2019 - Elsevier
Nimesulide is a relatively selective cyclooxygenase (COX)-2 inhibitor, non-steroidal anti-
inflammatory drug; it has been discovered in 1971 and firstly commercialized in Italy in 1985 …

Prostaglandin E2 and receptors: Insight into tumorigenesis, tumor progression, and treatment of hepatocellular carcinoma

C Chen, J Guan, X Gu, Q Chu, H Zhu - Frontiers in Cell and …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a common primary liver cancer with∼ 750,000 annual
incidence rates globally. PGE2, usually known as a pro-inflammatory cytokine, is over …

In silico environmental risk assessment of fate and effects of pharmaceuticals and their TPs generated and treated by coupling tertiary processes in hospital …

A Della-Flora, D Scunderlick, ML Wilde… - … : Water Research & …, 2023 - pubs.rsc.org
The solar photo-Fenton process leads to the formation of transformation products (TPs) that
are new compounds with an unknown chemical, physical, and biological characteristics …

Synthesis and different effects of biotinylated PAMAM G3 dendrimer substituted with nimesulide in human normal fibroblasts and squamous carcinoma cells

Ł Uram, A Filipowicz-Rachwał, M Misiorek, A Winiarz… - Biomolecules, 2019 - mdpi.com
Squamous cell carcinoma (SCC) remains a main cause of mortality in patients with neck and
head cancers, with poor prognosis and increased prevalence despite of available therapies …

Нестероидные противовоспалительные препараты: более 30 лет на пике актуальности

ОА Лесная - Трудный пациент, 2018 - cyberleninka.ru
Нестероидные противовоспалительные препараты (НПВП) являются наиболее часто
применяемыми в реальной клинической практике лекарственными средствами …

[HTML][HTML] Уменьшение гепатотоксичности нимесулида в составе композиции с глицирризинатом натрия, полученной механохимическим способом

ЕС Петрова, НА Жукова, ВИ Евсеенко… - Сибирский научный …, 2023 - cyberleninka.ru
Нимесулид (NIM)-это нестероидное противовоспалительное средство, действующее
специфически в качестве ингибитора циклооксигеназы 2 и широко используемое для …

Нимесулид: разнообразие терапевтических перспектив

ГИ ГРИДНЕВА - Эффективная фармакотерапия, 2019 - elibrary.ru
Нимесулид-один из наиболее широко применяемых нестероидных
противовоспалительных препаратов. Большой спектр эффектов и оптимальное …

Nimesulide Inhibits MAPK/COX-2 Pathway, and Prevents Oxidative Stress, Inflammation, and Apoptosis in Testes of Cisplatin-Challenged Rats

AA Fouad, HM Khalaf, UI Akl… - Journal of …, 2020 - classical.goforpromo.com
The potential testicular protective effect of nimesulide (NSE) was studied in cisplatin (CSP)-
challenged rats. NSE therapy (10 mg/kg/day, po) was applied for 15 days, and a single dose …