Ribosomes are a complex ensemble of rRNA and ribosomal proteins that function as mRNA
translation machines. Ribosome biogenesis is a multistep process that begins in the …

Ribosomal protein genes are among the most highly expressed genes in most cell types.
Their products are generally essential for ribosome synthesis, which is the cornerstone for …

Although high-throughput RNA sequencing (RNA-seq) has greatly advanced small non-
coding RNA (sncRNA) discovery, the currently widely used complementary DNA library …

Loss of sensory hair cells (HCs) in the mammalian inner ear leads to permanent hearing
and vestibular defects, whereas loss of HCs in zebrafish results in their regeneration. We …

SUMMARY In his 2001 article,“Translation: in retrospect and prospect,” the late Carl Woese
made a prescient observation that there was a need for the then-current view of translation …

Although several ribosomal protein paralogs are expressed in a tissue-specific manner, how
these proteins affect translation and why they are required only in certain tissues have …

While the molecular mechanism of autophagy is well studied, the cargoes delivered by
autophagy remain incompletely characterized. To examine the selectivity of autophagy …

Charophyceae are the most complex streptophyte algae, possessing tissue‐like structures,
rhizoids and a cellulose‐pectin‐based cell wall akin to embryophytes. Together with the …

Ribosomes are often seen as monolithic machines produced from uniformly regulated
genes. However, in yeast most ribosomal proteins come from duplicated genes. Here, we …

The nucleolus is the largest compartment of the eukaryotic cell's nucleus. It acts as a
ribosome factory, thereby sustaining the translation machinery. The nucleolus is also the …