C Junren, X Xiaofang, Z Huiqiong, L Gangmin… - Frontiers in …, 2021 - frontiersin.org
Hirudin, an acidic polypeptide secreted by the salivary glands of Hirudo medicinalis (also known as “Shuizhi” in traditional Chinese medicine), is the strongest natural specific inhibitor …
Due to the high recurrence rate and mortality of venous thrombosis, there is an urgent need for research on antithrombotic strategies. Because of the short half‐life, poor targeting …
RS Soumya, KG Raghu - Journal of Cardiology, 2023 - Elsevier
Nanoparticles are exclusively suitable for studying and developing potential therapies against cardiovascular diseases (CVD) because of their size, fine-tunable properties, and …
M Su, Q Dai, C Chen, Y Zeng, C Chu, G Liu - Nano-Micro Letters, 2020 - Springer
Thrombosis is a global health issue and one of the leading factors of death. However, its diagnosis has been limited to the late stages, and its therapeutic window is too narrow to …
L Zhang, Z Li, X Ye, Z Chen, ZS Chen - Drug Discovery Today, 2021 - Elsevier
Globally, the incidence of thromboembolic diseases has increased in recent years, accompanied by an increase in patient mortality. Currently, several targeting delivery …
Complications with atherosclerosis can often lead to fatal clot formation and blood vessel occlusion–also known as atherothrombosis. A key component to the development of …
X Lin, N Li, H Tang - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Stroke is a major public health issue, corresponding to the second cause of mortality and the first cause of severe disability. Ischemic stroke is the most common type of stroke …
A Yang, B Qiao, EM Strohm, J Cao, Z Wang… - Biomaterials …, 2020 - pubs.rsc.org
Although nanotechnology has shown great promise for treating multiple vascular diseases in recent years, simultaneous noninvasive detection and efficient dissolution of deep venous …
H Hu, H Wang, S Liang, X Li… - Journal of Biomaterials …, 2021 - Taylor & Francis
Abstract Poly (amido-amine)(PAMAM), one of the most widely studied dendrimers in the field of drug and gene delivery, can enhance the stability of DNA and deliver it to cell cytosol; …