The placenta is the site of connection between maternal and fetal circulation, and the liaison
is established early in pregnancy. A large variety of pregnancy complications such as …

Objective Findings from previous small studies have been reassuring regarding the safety of
treatment with hydroxychloroquine (HCQ) during pregnancy. In one recent study, it was …

Objectives To assess the infant risk of major congenital malformations (MCM) associated
with first-trimester exposure to hydroxychloroquine (HCQ) among mothers with systemic …

Objectives The aim of this study was to determine the risk of congenital malformations in
offspring born to women with systemic lupus erythematosus (SLE). Methods This nationwide …

Villitis of unknown etiology (VUE) is an inflammatory disease characterized by the infiltration
of maternal CD8+ T cells into the placental villi. Although the pathogenesis of VUE is still …

Many examples of the use of real-world data in the area of pharmacoepidemiology include
“big data” such as insurance claims, medical records, or hospital discharge databases …

Background A birth population-based study was conducted in Danyang, Jiangsu Province,
to evaluate major birth defects in emerging regions in China with similar maternal and …

Patients with rheumatic diseases frequently operate with incomplete or incorrect information
while planning for and experiencing pregnancy, often due to variability in provider care and …

Background Hydroxychloroquine (HCQ) is currently recommended for all pregnant women
with systemic lupus erythematosus (SLE) if tolerated. Some studies have reported an …

Background Access to quality disease information is one of the cornerstones of therapeutic
education and critical to help the doctor-patient dialog and adherence to treatment. Lupus …