Adaptive deep brain stimulation for movement disorders: the long road to clinical therapy

AC Meidahl, G Tinkhauser, DM Herz… - Movement …, 2017 - Wiley Online Library
Continuous high‐frequency DBS is an established treatment for essential tremor and
Parkinson's disease. Current developments focus on trying to widen the therapeutic window …

Deep brain stimulation for Tourette's syndrome

W Xu, C Zhang, W Deeb, B Patel, Y Wu, V Voon… - Translational …, 2020 - Springer
Tourette syndrome (TS) is a childhood-onset neuropsychiatric disorder characterized by the
presence of multiple motor and vocal tics. TS usually co-occurs with one or multiple …

Optimized programming algorithm for cylindrical and directional deep brain stimulation electrodes

DN Anderson, B Osting, J Vorwerk… - Journal of neural …, 2018 - iopscience.iop.org
Objective. Deep brain stimulation (DBS) is a growing treatment option for movement and
psychiatric disorders. As DBS technology moves toward directional leads with increased …

Magnetic control of a flexible needle in neurosurgery

A Hong, AJ Petruska, A Zemmar… - IEEE Transactions on …, 2020 - ieeexplore.ieee.org
Minimally invasive neurosurgery does not require large incisions and openings in the skull
to access the desired brain region, which often results in a faster recovery with fewer …

And then there was light: perspectives of optogenetics for deep brain stimulation and neuromodulation

J Delbeke, L Hoffman, K Mols, D Braeken… - Frontiers in …, 2017 - frontiersin.org
Deep Brain Stimulation (DBS) has evolved into a well-accepted add-on treatment for
patients with severe Parkinsons disease as well as for other chronic neurological conditions …

Proceedings of the seventh annual deep brain stimulation think tank: advances in neurophysiology, adaptive DBS, virtual reality, neuroethics and technology

A Ramirez-Zamora, J Giordano, A Gunduz… - Frontiers in human …, 2020 - frontiersin.org
The Seventh Annual Deep Brain Stimulation (DBS) Think Tank held on September 8th of
2019 addressed the most current:(1) use and utility of complex neurophysiological signals …

[HTML][HTML] Spatio-temporal dynamics of cortical drive to human subthalamic nucleus neurons in Parkinson's disease

A Sharott, A Gulberti, W Hamel, JA Köppen… - Neurobiology of …, 2018 - Elsevier
Pathological synchronisation of beta frequency (12–35 Hz) oscillations between the
subthalamic nucleus (STN) and cerebral cortex is thought to contribute to motor impairment …

Electrochemical evaluations of fractal microelectrodes for energy efficient neurostimulation

H Park, P Takmakov, H Lee - Scientific reports, 2018 - nature.com
Advancements in microfabrication has enabled manufacturing of microscopic
neurostimulation electrodes with smaller footprint than ever possible. The smaller electrodes …

Preliminary experience with a transcranial magnetic resonance–guided focused ultrasound surgery system integrated with a 1.5-T MRI unit in a series of patients with …

DG Iacopino, C Gagliardo, A Giugno… - Neurosurgical …, 2018 - thejns.org
OBJECTIVE Transcranial magnetic resonance–guided focused ultrasound surgery
(tcMRgFUS) is one of the emerging noninvasive technologies for the treatment of …

Model-based evaluation of closed-loop deep brain stimulation controller to adapt to dynamic changes in reference signal

F Su, K Kumaravelu, J Wang, WM Grill - Frontiers in neuroscience, 2019 - frontiersin.org
High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in
suppressing the motor symptoms of Parkinson's disease (PD). Current clinically-deployed …