High-throughput routes to biomaterials discovery
F Soheilmoghaddam, M Rumble… - Chemical …, 2021 - ACS Publications
Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …
or lost tissue and organ function, an unenviable situation only further exacerbated by a …
Architecture in 3D cell culture: An essential feature for in vitro toxicology
SA Lelièvre, T Kwok, S Chittiboyina - Toxicology in vitro, 2017 - Elsevier
Three-dimensional cell culture has the potential to revolutionize toxicology studies by
allowing human-based reproduction of essential elements of organs. Beyond the study of …
allowing human-based reproduction of essential elements of organs. Beyond the study of …
Time series modeling of live-cell shape dynamics for image-based phenotypic profiling
Live-cell imaging can be used to capture spatio-temporal aspects of cellular responses that
are not accessible to fixed-cell imaging. As the use of live-cell imaging continues to …
are not accessible to fixed-cell imaging. As the use of live-cell imaging continues to …
Cigarette smoke and e-cigarette vapor dysregulate osteoblast interaction with titanium dental implant surface
M Rouabhia, H Alanazi, HJ Park… - Journal of Oral …, 2019 - meridian.allenpress.com
The purpose of this study was to determine the possible deleterious effects of e-cigarette
vapor on osteoblast interaction with dental implant material. Osteoblasts were cultured onto …
vapor on osteoblast interaction with dental implant material. Osteoblasts were cultured onto …
Optimization of polymer-ECM composite scaffolds for tissue engineering: effect of cells and culture conditions on polymeric nanofiber mats
The design of composite tissue scaffolds containing an extracellular matrix (ECM) and
synthetic polymer fibers is a new approach to create bioactive scaffolds that can enhance …
synthetic polymer fibers is a new approach to create bioactive scaffolds that can enhance …
Profiling stem cell states in three-dimensional biomaterial niches using high content image informatics
A predictive framework for the evolution of stem cell biology in 3-D is currently lacking. In this
study we propose deep image informatics of the nuclear biology of stem cells to elucidate …
study we propose deep image informatics of the nuclear biology of stem cells to elucidate …
Engineering lineage potency and plasticity of stem cells using epigenetic molecules
Stem cells are considered as a multipotent regenerative source for diseased and
dysfunctional tissues. Despite the promise of stem cells, the inherent capacity of stem cells to …
dysfunctional tissues. Despite the promise of stem cells, the inherent capacity of stem cells to …
High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation
Stem and progenitor cells that exhibit significant regenerative potential and critical roles in
cancer initiation and progression remain difficult to characterize. Cell fates are determined …
cancer initiation and progression remain difficult to characterize. Cell fates are determined …
Convergence of highly resolved and rapid screening platforms with dynamically engineered, cell phenotype-prescriptive biomaterials
Biophysical and biochemical cues from the cellular microenvironment initiate intracellular
signaling through cellular membrane receptors and trigger specific cell developmental …
signaling through cellular membrane receptors and trigger specific cell developmental …
[图书][B] Fluorescence Imaging Based Analysis of Actin Turnover: Longitudinal Profiling of Stem Cell Phenotypes During Differentiation
P Mishra - 2020 - search.proquest.com
Stem cells derived from adults have become the focal point of cell-based regenerative
therapies. The most commonly used stem cells, mesenchymal stem cells (abbreviated …
therapies. The most commonly used stem cells, mesenchymal stem cells (abbreviated …