Genetic and biological hallmarks of colorectal cancer

J Li, X Ma, D Chakravarti, S Shalapour… - Genes & …, 2021 - genesdev.cshlp.org
Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

Dysbiosis and the immune system

M Levy, AA Kolodziejczyk, CA Thaiss… - Nature Reviews …, 2017 - nature.com
Throughout the past century, we have seen the emergence of a large number of
multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and …

Plant-derived exosomal microRNAs shape the gut microbiota

Y Teng, YI Ren, M Sayed, X Hu, C Lei, A Kumar… - Cell host & …, 2018 - cell.com
The gut microbiota can be altered by dietary interventions to prevent and treat various
diseases. However, the mechanisms by which food products modulate commensals remain …

The microbiome and innate immunity

CA Thaiss, N Zmora, M Levy, E Elinav - Nature, 2016 - nature.com
The intestinal microbiome is a signalling hub that integrates environmental inputs, such as
diet, with genetic and immune signals to affect the host's metabolism, immunity and …

Comparing early life nutritional sources and human milk feeding practices: personalized and dynamic nutrition supports infant gut microbiome development and …

SR Ames, LC Lotoski, MB Azad - Gut Microbes, 2023 - Taylor & Francis
Exclusive breastfeeding is recommended for the first six months of life, but many infants
receive pumped milk, formula, donor human milk, or other nutritional sources during this …

Human immunology and immunotherapy: main achievements and challenges

J Varadé, S Magadán… - Cellular & Molecular …, 2021 - nature.com
The immune system is a fascinating world of cells, soluble factors, interacting cells, and
tissues, all of which are interconnected. The highly complex nature of the immune system …

[HTML][HTML] Role of the normal gut microbiota

SM Jandhyala, R Talukdar… - World journal of …, 2015 - ncbi.nlm.nih.gov
Relation between the gut microbiota and human health is being increasingly recognised. It
is now well established that a healthy gut flora is largely responsible for overall health of the …

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

TG Dinan, JF Cryan - The Journal of physiology, 2017 - Wiley Online Library
There is a growing realisation that the gut–brain axis and its regulation by the microbiota
may play a key role in the biological and physiological basis of neurodevelopmental, age …

Human breast milk: from food to active immune response with disease protection in infants and mothers

GAG Lokossou, L Kouakanou, A Schumacher… - Frontiers in …, 2022 - frontiersin.org
Breastfeeding is associated with long-term wellbeing including low risks of infectious
diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases …