Immune dysregulation is an important component of the pathophysiology of COVID-19. A
large body of literature has reported the effect of immune-based therapies in patients with …

Children and adolescents infected with severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are predominantly asymptomatic or have mild symptoms compared with the …

As severe acute respiratory syndrome coronavirus 2 continues to spread worldwide, there
have been increasing reports from Europe, North America, Asia, and Latin America …

Abstract Multisystem Inflammatory Syndrome in Children (MIS-C) is a new phenomenon
reported worldwide with temporal association with Covid-19. The objective of this paper is to …

Multisystem inflammatory syndrome (MIS-C) is a pediatric hyperinflammation disorder
caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It has now been …

Summary Background In April, 2020, clinicians in the UK observed a cluster of children with
unexplained inflammation requiring admission to paediatric intensive care units (PICUs). We …

An association between a novel pediatric hyperinflammatory condition and SARS-CoV-2
was recently published and termed pediatric inflammatory multisystem syndrome, temporally …

Recent reports highlight a new clinical syndrome in children related to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2)—multisystem inflammatory syndrome in …

Background A multisystem inflammatory syndrome in children (MIS-C) is associated with
coronavirus disease 2019. The New York State Department of Health (NYSDOH) …

Initial reports on COVID-19 described children as largely spared from severe manifestations,
with only 2–6% of children requiring intensive care treatment. However, since mid-April …