Isothiazoles in the design and synthesis of biologically active substances and ligands for metal complexes

AV Kletskov, NA Bumagin, FI Zubkov, DG Grudinin… - …, 2020 - thieme-connect.com
The chemistry of isothiazoles is being intensively developed, which is evidenced by the wide
range of selective transformations involving the isothiazole heterocycle and the high …

Acetylcoumarin in cyclic and heterocyclic-containing coumarins: Synthesis and biological applications

NH Nasab, F Azimian, HG Kruger, SJ Kim - Tetrahedron, 2022 - Elsevier
In design and development of bioactive compounds, coumarins as ubiquitous natural
heterocyclic compounds have been widely used. In particular, the combination of the …

Ruthenium (II) complexes of Isothiazole Ligands: crystal structure, HSA/DNA interactions, cytotoxic activity and molecular docking simulations

MB Djukić, MS Jeremić, IP Filipović… - …, 2020 - Wiley Online Library
Two new neutral ruthenium (II) complexes [Ru (η6‐p‐cymene) Cl2 (1)](3) and [Ru (η6‐p‐
cymene) Cl2 (2)](4)(1= 5‐(phenylamino)‐3‐pyrrolidin‐1‐ylisothiazole‐4‐carbonitrile; 2= 3 …

Identification of novel pyrazole and benzimidazole based derivatives as PBP2a inhibitors: Design, synthesis, and biological evaluation

MAW Shalaby, EME Dokla, RAT Serya… - … Sciences Ain Shams …, 2019 - journals.ekb.eg
The antibiotic resistance of methicillin-resistant Staphylococcus aureus (MRSA) is
attributable to the expression of the high molecular mass transpeptidase enzyme, penicillin …

The 5-hydrazino-3-methylisothiazole-4-carboxylic acid, its new 5-substituted derivatives and their antiproliferative activity

I Jęśkowiak, M Mączyński, J Trynda, J Wietrzyk… - Bioorganic …, 2019 - Elsevier
Currently, the basic method of treatment of colon cancer is surgery. The range of anticancer
drugs used in the treatment of colorectal cancer is small and is based mainly on systemic …

The N'-Substituted Derivatives of 5-Chloro-3-Methylisothiazole-4-Carboxylic Acid Hydrazide with Antiproliferative Activity

I Jęśkowiak, S Ryng, M Świtalska, J Wietrzyk, I Bryndal… - Molecules, 2019 - mdpi.com
Thanks to the progress in oncology, pharmacological treatment of cancer is gaining in
importance and in the near future anti-cancer chemotherapeutics are expected to be the …

Isothiazoles: Synthetic Strategies and Pharmacological Applications

NA Sasane, HN Akolkar, NR Darekar, VM Khedkar… - 2024 - books.rsc.org
In the contemporary organic synthesis, aromatic heterocycles have been considered
invaluable compounds for the production of drugs, pharmaceutical intermediates, organic …

Synthesis, Properties, and Therapeutic Applications of Dithiazoles

S Barick, TK Sagar, S Chandrashekharappa - 2024 - books.rsc.org
Heterocycles have been the subject of extensive organic1–8 and medicinal chemistry9–16
research for almost a century. They have contributed to the biological17–19 and industrial …

[PDF][PDF] Strukturna, teorijska i biološka ispitivanja kompleksa rutenijuma (II) sa derivatima imidazola i izotiazola

M Đukić - 2021 - nardus.mpn.gov.rs
СТРУКТУРНА, ТЕОРИЈСКА И БИОЛОШКА ИСПИТИВАЊА КОМПЛЕКСА РУТЕНИЈУМА(II)
С Page 1 УНИВЕРЗИТЕТ У КРАГУЈЕВЦУ ПРИРОДНО-МАТЕМАТИЧКИ ФАКУЛТЕТ Маја …

Структурна, Теоријска И Биолошка Испитивања Комплекса Рутенијума (II) Са Дериватима Имидазола И Изотиазола

МБ Ђукић - 2021 - search.proquest.com
У оквиру ове докторске дисертације синтетисани су и окарактерисани комплекси
рутенијума (II) са имидазолима ([Ru (η 6-p-cymene)(N-MeIm) 3] Cl 2· 2H 2 O и [Ru (η 6 …