In this review, we focus on a group of mobile genetic elements designated pathogenicity
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …

Recombination is typically thought of as a symmetrical process resulting in large-scale
reciprocal genetic exchanges between homologous chromosomes. Recombination events …

The sequence of the mouse genome is a key informational tool for understanding the
contents of the human genome and a key experimental tool for biomedical research. Here …

INTRODUCTION Crocodilians and birds are the two extant clades of archosaurs, a group
that includes the extinct dinosaurs and pterosaurs. Fossils suggest that living crocodilians …

Abstract Analysis of Hi-C data has shown that the genome can be divided into two
compartments called A/B compartments. These compartments are cell-type specific and are …

908 N. Galtier et al. metes averaged over germ cells remain Mendelian. If, however, the
repair process is biased toward, say, G: C pairs, then allele frequencies would evolve in a …

Processed pseudogenes were created by reverse-transcription of mRNAs; they provide
snapshots of ancient genes existing millions of years ago in the genome. To find them in the …

The nuclear genomes of vertebrates are mosaics of isochores, very long stretches (≫
300kb) of DNA that are homogeneous in base composition and are compositionally …

As whole-genome sequencing becomes commoditized and we begin to sequence and
analyze personal genomes for clinical and diagnostic purposes, it is necessary to …

Recent studies on the genomes of protists, plants, fungi and animals confirm that the
increase in genome size and gene number in different eukaryotic lineages is paralleled by a …