Tularaemia is a zoonotic disease caused by Francisella tularensis, a Gram-negative,
facultative intracellular bacterium. Typically, human and animal infections are caused by F …

The earth contains a huge number of largely uncharacterized Bacteria and Archaea.
Microbiologists are struggling to summarize their genetic diversity and classify them, which …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Macrophages respond to cytosolic nucleic acids by activating cysteine protease caspase-1
within a complex called the inflammasome. Subsequent cleavage and secretion of …

Tularemia is a bacterial disease of humans, wild, and domestic animals. Francisella
tularensis, which is a Gram-negative coccobacillus-shaped bacterium, is the causative agent …

The inflammasome is a signalling platform leading to caspase-1 activation. Caspase-1
causes pyroptosis, a necrotic-like cell death. AIM2 is an inflammasome sensor for cytosolic …

The bacterium Francisella tularensis causes the vector-borne zoonotic disease tularemia,
and may infect a wide range of hosts including invertebrates, mammals and birds …

Among blood-sucking arthropods, ticks are recognized as being of prime global importance
because of their role as vectors of pathogens affecting human and animal health. Ticks carry …

Tularemia is considered to have existed in Anatolia for several thousand years. There are
suspicions regarding its use in biological warfare in the Neshite-Arzawan conflict. The …

Maintenance of membrane function is essential and regulated at the genomic,
transcriptional, and translational levels. Bacterial pathogens have a variety of mechanisms …