Deep brain stimulation for dystonia

M Vidailhet, MF Jutras, E Roze, D Grabli - Handbook of clinical neurology, 2013 - Elsevier
The few reported controlled studies show that bilateral stimulation of the globus pallidus
interna (GPi) is a safe and effective long-term treatment for hyperkinetic disorders. However …

Pallidal deep brain stimulation for monogenic dystonia: the effect of gene on outcome

S Tisch, KR Kumar - Frontiers in neurology, 2021 - frontiersin.org
Globus pallidus internus deep brain stimulation (GPi DBS) is the most effective intervention
for medically refractory segmental and generalized dystonia in both children and adults …

Deep brain stimulation: current and future clinical applications

MK Lyons - Mayo Clinic Proceedings, 2011 - Elsevier
Deep brain stimulation (DBS) has developed during the past 20 years as a remarkable
treatment option for several different disorders. Advances in technology and surgical …

Myoclonic disorders: a practical approach for diagnosis and treatment

M Kojovic, C Cordivari, K Bhatia - Therapeutic advances in …, 2011 - journals.sagepub.com
Myoclonus is a sudden, brief, involuntary muscle jerk. It is caused by abrupt muscle
contraction, in the case of positive myoclonus, or by sudden cessation of ongoing muscular …

Which patients with dystonia benefit from deep brain stimulation? A metaregression of individual patient outcomes

C Andrews, I Aviles-Olmos, M Hariz… - Journal of Neurology …, 2010 - jnnp.bmj.com
There is substantial variability in the responsiveness of dystonia patients to deep brain
stimulation (DBS), presumably due to the multiple causes of dystonia. This article presents …

Treatment of dystonia with deep brain stimulation

JL Ostrem, PA Starr - Neurotherapeutics, 2008 - Springer
Pallidal deep brain stimulation (DBS) is an established treatment option for medically
refractive dystonia. The mechanism by which globus pallidus pars interna (GPi) DBS …

Myoclonus‐dystonia: an update

K Kinugawa, M Vidailhet, F Clot, E Apartis… - Movement …, 2009 - Wiley Online Library
Our knowledge of the clinical, neurophysiological, and genetic aspects of myoclonus‐
dystonia (M‐D) has improved markedly in the recent years. Basic research has provided …

It's not just the basal ganglia: cerebellum as a target for dystonia therapeutics

A Tewari, R Fremont, K Khodakhah - Movement Disorders, 2017 - Wiley Online Library
Dystonia is a common movement disorder that devastates the lives of many patients, but the
etiology of this disorder remains poorly understood. Dystonia has traditionally been …

Pallidal and thalamic deep brain stimulation in myoclonus‐dystonia

D Gruber, AA Kühn, T Schoenecker, A Kivi… - Movement …, 2010 - Wiley Online Library
Deep brain stimulation (DBS) of the internal globus pallidus (GPi) and ventral intermediate
thalamic nucleus (VIM) are established treatment options in primary dystonia and tremor …

Myoclonus: pathophysiology and treatment options

A Levy, R Chen - Current treatment options in neurology, 2016 - Springer
Opinion statement Treatment of myoclonus requires an understanding of the
physiopathology of the condition. The first step in treatment is to determine if there is an …