Management of acute ischemic stroke

MS Phipps, CA Cronin - Bmj, 2020 - bmj.com
Stroke is the leading cause of long term disability in developed countries and one of the top
causes of mortality worldwide. The past decade has seen substantial advances in the …

Primary and Secondary Prevention of Ischemic Stroke and Cerebral Hemorrhage: JACC Focus Seminar

HC Diener, GJ Hankey - Journal of the American College of Cardiology, 2020 - jacc.org
Stroke is a leading cause of permanent disability. Therefore, primary prevention of first
stroke and secondary prevention of recurrent stroke are a high priority. Primary prevention of …

Editor's Choice–European Society for Vascular Surgery (ESVS) 2023 clinical practice guidelines on the management of atherosclerotic carotid and vertebral artery …

R Naylor, B Rantner, S Ancetti, GJ de Borst… - European Journal of …, 2023 - ejves.com
These guidelines will be updated every four years. Vascular centres are encouraged to audit
implementations made as a result of the guidelines. Audit cycles should be repeated and …

Falling stroke rates during COVID-19 pandemic at a comprehensive stroke center

JE Siegler, ME Heslin, L Thau, A Smith… - Journal of Stroke and …, 2020 - Elsevier
Introduction Although there is evidence to suggest a high rate of cerebrovascular
complications in patients with SARS-CoV-2 infection, anecdotal reports indicate a falling rate …

[PDF][PDF] Outcomes associated with clopidogrel-aspirin use in minor stroke or transient ischemic attack: a pooled analysis of Clopidogrel in High-Risk Patients With Acute …

Y Pan, JJ Elm, H Li, JD Easton, Y Wang… - JAMA …, 2019 - jamanetwork.com
Importance Dual antiplatelet therapy with clopidogrel and aspirin is effective for secondary
prevention after minor ischemic stroke or transient ischemic attack (TIA). Uncertainties …

Diagnosis and management of acute ischaemic stroke

R Hurford, A Sekhar, TAT Hughes, KW Muir - Practical Neurology, 2020 - pn.bmj.com
Acute ischaemic stroke is a major public health priority and will become increasingly
relevant to neurologists of the future. The cornerstone of effective stroke care continues to be …

Safety and efficacy of factor XIa inhibition with milvexian for secondary stroke prevention (AXIOMATIC-SSP): a phase 2, international, randomised, double-blind …

M Sharma, CA Molina, K Toyoda, D Bereczki… - The Lancet …, 2024 - thelancet.com
Background People with factor XI deficiency have lower rates of ischaemic stroke than the
general population and infrequent spontaneous bleeding, suggesting that factor XI has a …

Antiplatelet use in ischemic stroke

M Kamarova, S Baig, H Patel, K Monks… - Annals of …, 2022 - journals.sagepub.com
Objective: A literature review of antiplatelet agents for primary and secondary stroke
prevention, including mechanism of action, cost, and reasons for lack of benefit. Data …

[HTML][HTML] Dual antiplatelet therapies and causes in minor stroke or transient ischemic attack: a prespecified analysis in the CHANCE-2 Trial

X Xie, J Jing, X Meng, SC Johnston, PM Bath, Z Li… - Stroke, 2023 - journals.lww.com
BACKGROUND: It is unclear whether patients with different stroke/transient ischemic attack
etiologies benefit differently from gene-directed dual antiplatelet therapy. This study …

Secretory SERPINE1 expression is increased by antiplatelet therapy, inducing MMP1 expression and increasing colon cancer metastasis

WT Kim, JY Mun, SW Baek, MH Kim, GE Yang… - International journal of …, 2022 - mdpi.com
Contrary to many reports that antiplatelet agents inhibit cancer growth and metastasis, new
solid tumors have been reported in patients receiving long-term antiplatelet therapy. We …