Mutational Signatures in Gastric Cancer and Their Clinical Implications
P Pužar Dominkuš, P Hudler - Cancers, 2023 - mdpi.com
Simple Summary There is a lack of molecular biomarkers that would allow better
characterisation and categorisation of gastric tumours. Distinct mutational patterns have …
characterisation and categorisation of gastric tumours. Distinct mutational patterns have …
[HTML][HTML] Genomic and transcriptomic profiling indicates the prognosis significance of mutational signature for TMB-high subtype in Chinese patients with gastric cancer
Y Cheng, D Bu, Q Zhang, R Sun, S Lyle, G Zhao… - Journal of advanced …, 2023 - Elsevier
Introduction Gastric cancer (GC) is the third leading cause of cancer-related deaths in China
and immunotherapy emerging as a revolutionary treatment for GC recently. Tumor …
and immunotherapy emerging as a revolutionary treatment for GC recently. Tumor …
Interleukin‑17 activates JAK2/STAT3, PI3K/Akt and nuclear factor‑κB signaling pathway to promote the tumorigenesis of cervical cancer
Y Bai, H Li, R Lv - Experimental and Therapeutic …, 2021 - spandidos-publications.com
Abstract Interleukin (IL)‑17 has been regarded as a significant factor in inflammation. In
addition, IL‑17 is known to be involved in the progression of cancers; however, the function …
addition, IL‑17 is known to be involved in the progression of cancers; however, the function …
Relating mutational signature exposures to clinical data in cancers via signeR 2.0
RD Drummond, A Defelicibus, M Meyenberg… - BMC …, 2023 - Springer
Background Cancer is a collection of diseases caused by the deregulation of cell processes,
which is triggered by somatic mutations. The search for patterns in somatic mutations, known …
which is triggered by somatic mutations. The search for patterns in somatic mutations, known …
A signature of Ten Chromodomain Helicase DNA (CHD) Genes Related LncRNAs Predicts Overall Survival in Gastric Cancer Patients
Y Li - 2021 - researchsquare.com
Background: Gastric cancer (GC) is one of the most common tumors in the world and is often
found at an advanced stage. Gene mutations and changes in lncRNA expression often led …
found at an advanced stage. Gene mutations and changes in lncRNA expression often led …