Inflammation is increasingly recognized as being a critical contributor to both normal
development and injury outcome in the immature brain. The focus of this Review is to …

Increasing evidence underlines that prototypical inflammatory cytokines (IL-1β, TNF-α and IL-
6) either synthesized in the central (CNS) or peripheral nervous system (PNS) by resident …

Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Perinatal hypoxia-ischemia remains the primary cause of acute neonatal brain injury,
leading to a high mortality rate and long-term neurological deficits, such as behavioral …

Inflammation plays a critical role in mediating brain injury induced by neonatal hypoxic
ischemic encephalopathy (HIE). The mechanisms underlying inflammatory responses to …

During early post-natal life, neonates must adjust to the transition from the sheltered intra-
uterine environment to the microbe-laden external world, wherein they encounter a …

Hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of morbidity and
mortality in neonates. Because of high concentrations of sensitive immature cells, metal …

MN-V, SP, SAR, SG, and SC designed the research studies; MN-V., P.-YC, LB, M.-ÈB, SP,
MHB, AM, AB-R., DJS, AL-M., XH, A. Boudreault, AC, IB, and SG conducted experiments; …

Preterm birth is a major contributor to neonatal morbidity and mortality. Complications of
prematurity such as bronchopulmonary dysplasia (BPD, affecting the lung), pulmonary …

Lead (Pb) is a heavy metal with a proven neurotoxic effect. Exposure is particularly
dangerous to the developing brain in the pre-and neonatal periods. One postulated …