Kidney perfusion as an organ quality assessment tool—are we counting our chickens before they have hatched?

J De Beule, I Jochmans - Journal of Clinical Medicine, 2020 - mdpi.com
The final decision to accept an organ for transplantation remains a subjective one. With
“poor organ quality” commonly cited as a major reason for kidney discard, accurate …

A roadmap for innovation to advance transplant access and outcomes: a position statement from the National Kidney Foundation

KL Lentine, S Pastan, S Mohan, PP Reese… - American Journal of …, 2021 - Elsevier
Over the past 65 years, kidney transplantation has evolved into the optimal treatment for
patients with kidney failure, dramatically reducing suffering through improved survival and …

Disparities in acceptance of deceased donor kidneys between the United States and France and estimated effects of increased US acceptance

O Aubert, PP Reese, B Audry, Y Bouatou… - JAMA internal …, 2019 - jamanetwork.com
Importance Approximately 3500 donated kidneys are discarded in the United States each
year, drawing concern from Medicare and advocacy groups. Objective To estimate the …

The impact of kidney donor profile index on delayed graft function and transplant outcomes: a single‐center analysis

TJ Zens, JS Danobeitia, G Leverson… - Clinical …, 2018 - Wiley Online Library
Introduction Renal transplant outcomes result from a combination of factors. Traditionally,
donor factors were summarized by classifying kidneys as extended criteria or standard …

Who can tolerate a marginal kidney? Predicting survival after deceased donor kidney transplant by donor–recipient combination

S Bae, AB Massie, AG Thomas, G Bahn… - American Journal of …, 2019 - Wiley Online Library
The impact of donor quality on post–kidney transplant (KT) survival may vary by candidate
condition. Characterizing this variation would increase access to KT without sacrificing …

ISHLT consensus statement on donor organ acceptability and management in pediatric heart transplantation

R Kirk, AI Dipchand, RR Davies, O Miera… - The Journal of Heart and …, 2020 - Elsevier
The number of potential pediatric heart transplant recipients continues to exceed the number
of donors, and consequently the waitlist mortality remains significant. Despite this, around …

[HTML][HTML] Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys

JR DiRito, SA Hosgood, M Reschke, C Albert… - American Journal of …, 2021 - Elsevier
Thousands of kidneys from higher-risk donors are discarded annually because of the
increased likelihood of complications posttransplant. Given the severe organ shortage, there …

[HTML][HTML] Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation

JM Kaths, M Hamar, J Echeverri, I Linares… - American Journal of …, 2018 - Elsevier
Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft
preservation and functional improvement in kidney transplantation. We investigated whether …

Validation of the Kidney Donor Profile Index (KDPI) to assess a deceased donor's kidneys' outcome in a European cohort

M Dahmen, F Becker, H Pavenstädt, B Suwelack… - Scientific reports, 2019 - nature.com
Abstract The Kidney Donor Profile Index (KDPI) was introduced in the United States in 2014
to guide the decision making of clinicians with respect to accepting or declining a donated …

[HTML][HTML] Deceased-donor acute kidney injury is not associated with kidney allograft failure

IE Hall, E Akalin, JS Bromberg, MD Doshi, T Greene… - Kidney international, 2019 - Elsevier
Deceased-donor acute kidney injury (AKI) is associated with organ discard and delayed
graft function, but data on longer-term allograft survival are limited. We performed a …