High-throughput single cell imaging is a critical enabling and driving technology in
molecular and cellular biology, biotechnology, medicine and related areas. Imaging flow …

Highlights•Microfluidic strategies for cell focusing are beneficial for the precise and accurate
characterization of single cells in flow.•Camera-based imaging flow cytometers provide ultra …

When challenged by hypertonicity, dehydrated cells must recover their volume to survive.
This process requires the phosphorylation-dependent regulation of SLC12 cation chloride …

Immune thrombocytopenia (ITP) is a prevalent autoimmune disease characterized by
autoantibody-induced platelet clearance. Some ITP patients are refractory to standard …

To reduce attrition in drug development, it is crucial to consider the development and
implementation of translational phenotypic assays as well as decipher diverse molecular …

Starvation is a strong physiological stimulus of macroautophagy/autophagy. In this study, we
addressed the question as to whether it would be possible to measure autophagy in blood …

Holographic cytometry is introduced as an ultra-high throughput implementation of
quantitative phase imaging of single cells flowing through parallel microfluidic channels …

Coronary artery disease (CAD) is characterised by progressive atherosclerotic plaque
leading to flow-limiting stenosis, while myocardial infarction (MI) occurs due to plaque …

Background Malignant gliomas are rapidly progressive brain tumors with high mortality.
Fluorescence guided surgery (FGS) with 5-aminolevulinic acid (5-ALA) provides fluorescent …

Circulating large “preplatelets” undergo fission via barbell platelet intermediates into two
smaller, mature platelets. In this study, we determine whether preplatelets and/or barbells …